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Fibroblast inhibitors assist anti-cancer drugs to suppress cancer growth
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Fibroblast inhibitors assist anti-cancer drugs to suppress cancer growth

by  American Institute of Physics A 3D co-culture system mimics the tumor microenvironment for studying the impact of drug combinations. An anti-fibrotic drug, nintedanib, could improve the effect of an anti-cancer drug, cisplatin, to reduce tumor growth and invasion. Credit: Huei-Jyuan Pan Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the...