July 11, 2018 by Chris Waters, The Conversation Maybe you’ve had the experience of wading in a stream and struggling to keep your balance on the slick rocks, or forgetting to brush your teeth in the morning and feeling a slimy coating in your mouth. These are examples of bacterial biofilms that are found anywhere a surface is...
Tag: <span>Fibrosis</span>
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Metformin reverses established lung fibrosisc
Researchers at the University of Alabama at Birmingham have shown—for the first time—that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism. Jaroslaw Zmijewski and Victor Thannickal. Credit: UAB This novel finding, reported in the journal Nature Medicine, is important because, despite significant advances to reveal the pathological mechanisms of persistent fibrosis,...
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Lipid-based nanoparticles enable improved therapy for cystic fibrosis patients
OREGON STATE UNIVERSITY PORTLAND, Ore. – Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients. Cystic fibrosis is a progressive genetic disorder that results in persistent lung infection and afflicts 30,000 people in the U.S., with about 1,000...
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Researchers suppress fibrosis chemical signal to block haywire healing
Fibroblasts are cells within our connective tissue. They help maintain tissue scaffolding through production of collagen and other fibers. When pushed to action (induced) by TGF-beta, fibroblasts respond by producing stress fibers. In the …more An injured body always seeks to heal. But that process is far from simple. A host of cells organize to...
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Fibrosis reversed when ‘don’t eat me’ signal blocked, study finds
A chest radiograph of a patient with Idiopathic Pulmonary Fibrosis (IPF). Credit: Wikipedia/CC BY-SA 3.0 Researchers at the Stanford University School of Medicine have identified a pathway that, when mutated, drives fibrosis in many organs of the body. The pathway underlies what have been considered somewhat disparate conditions, including scleroderma, idiopathic pulmonary fibrosis, liver cirrhosis, kidney...