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Researchers develop first inhibitors against key epigenetic complex involved in cancer
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Researchers develop first inhibitors against key epigenetic complex involved in cancer

Leukemia stem cells are rare cells that can renew themselves while continuing to generate malignant cells known as leukemic blasts. These cells are difficult to eradicate using chemotherapy drugs and frequently lead to the recurrence of leukemia. Leukemia stem cells, however, are dependent on a protein complex called polycomb repressive complex 1, or PRC1, which...