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Blocking FNDC5, the precursor of the exercise hormone irisin, protects mice from cancer-induced cachexia
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Blocking FNDC5, the precursor of the exercise hormone irisin, protects mice from cancer-induced cachexia

by American Society for Bone and Mineral Research  Credit: Pixabay/CC0 Public Domain The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found. When cancer patients develop cachexia, their...