by Jeni Bushman, University of Illinois at Urbana-Champaign Summary of the effects from activation of mGluR7 on molecular and behavioral deficits in Fmr1 KO mice. Credit: EMBO Molecular Medicine (2024). DOI: 10.1038/s44321-024-00038-wFragile X syndrome is one of the most commonly inherited forms of autism and intellectual disability, and no treatment currently exists. But a team of...
by American Heart Association Credit: Pixabay/CC0 Public Domain A new study in mice has identified FXR1, a protein in the same family as the one implicated in Fragile X syndrome, as a potential target for creating a new type of blood pressure-lowering medicine, according to preliminary research presented at the American Heart Association’s Vascular Discovery: From...
RUSH UNIVERSITY MEDICAL CENTER An experimental treatment produced improvements in cognitive function and language in patients with fragile X syndrome, according to study results published on April 29 in Nature Medicine. Fragile X syndrome (known as FXS for short) is the most common known genetic cause of autism and the most common cause of inherited intellectual...
by Peter Jurich, University of Wisconsin-Madison Credit: Pixabay/CC0 Public Domain An analysis of electronic health records for 1.7 million Wisconsin patients revealed a variety of health problems newly associated with fragile X syndrome, the most common inherited cause of intellectual disability and autism, and may help identify cases years in advance of the typical clinical diagnosis. Researchers from...
by Massachusetts Institute of Technology MIT scientists have identified a potential new strategy for treating Fragile X syndrome, a disorder that is the leading heritable cause of intellectual disability and autism. In a study of mice, the researchers showed that inhibiting an enzyme called GSK3 alpha reversed many of the behavioral and cellular features of...
NIH/EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT Researchers have developed a test to measure the expressive language skills of people with Fragile X syndrome, a genetic disorder that may result in intellectual disability, cognitive impairment and symptoms of autism spectrum disorder. Expressive language refers to the use of words to convey...
NIH/EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT Researchers have developed a test to measure the expressive language skills of people with Fragile X syndrome, a genetic disorder that may result in intellectual disability, cognitive impairment and symptoms of autism spectrum disorder. Expressive language refers to the use of words to convey...
