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Small change makes cancer vaccine more effective in animal tests

Tweaking the adenovirus spike protein induces a more robust immune reaction for a cancer vaccine against gastric, pancreatic, esophageal and colon malignancies in animal models. THOMAS JEFFERSON UNIVERSITY PHILADELPHIA – Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine...

Major weight loss—whether from surgery or diet—has same metabolic benefits
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Major weight loss—whether from surgery or diet—has same metabolic benefits

by Washington University School of Medicine Gastric bypass surgery is the most effective therapy to treat or reverse type 2 diabetes in severely obese patients. A longstanding theory has suggested that the operation may have unique, weight loss-independent effects in treating diabetes. But new research from Washington University School of Medicine in St. Louis indicates...

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MRI effective for monitoring liver fat in obese patients

OAK BROOK, Ill. – MRI provides a safe, noninvasive way to monitor liver fat levels in people who undergo weight loss treatments for obesity, according to a new study published in the journal Radiology. Obesity is a major U.S. public health issue, with more than two-thirds of American adults considered overweight or obese. Non-alcoholic fatty...

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Scientists identify genetic marker for gastric cancer prognosis

Although immunotherapy is seen as a very promising treatment for cancer, currently only 20 to 30 percent of patients respond positively. Being able to identify the people most likely to benefit from the costly therapy is a Holy Grail for oncologists. Histopathology of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric...