(© DOC RABE Media – stock.adobe.com)HEALTH & MEDICAL NEWS by Chris Melore MAY 14, 2024 SEATTLE — A revolutionary new treatment may forever get rid of the painful and embarrassing blisters that come from a herpes flare-up. The herpes viruses that cause either cold sores around the mouth or blisters near the genitals stick around...
by Max Delbrück Center for Molecular Medicine Mutated T cells are unable to kill B cells (red) induced by the Epstein-Barr virus. This causes other immune cells to flow into the area of infection, thereby blocking a blood vessel (center). Credit: Elijah D. Lowenstein and Xun Li, K. Rajewsky Lab, Max Delbrück CenterSome hereditary genetic defects...
by University of Auckland Credit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher of a trial published in the New England Journal of Medicine. The patients from New Zealand, the Netherlands and the UK have...
By Carolyn Y. JohnsonJuly 6, 2023 at 2:00 p.m. EDT Researchers using modern gene-editing tools have discovered that the intuition of scientists from more than a century ago was right: Cells with unusual numbers of chromosomes are drivers of cancer. The study, published Thursday in the journal Science, renews scientific attention on an old-fashioned idea, one that could point...
by Temple University Credit: CC0 Public Domain Gene-editing therapy aimed at two targets—HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells—can effectively eliminate HIV infection, new research from the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) shows. The study, published online...
By Paul McClure April 30, 2023 Researchers used virus-based protein fragments called peptides to guide CRISPR/Cas molecules into cells Depositphotos Researchers have developed a highly efficient new gene-editing method that uses virus-based protein fragments. The method could be used to level up existing cell and gene therapies used to treat cancer and other diseases. Using CRISPR...
MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA — Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins. With further development, these particles could offer an inhalable treatment for cystic fibrosis and other...
INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: GENE EDITING VIA CRISPR/CAS9 CAN LEAD TO CELL TOXICITY AND GENOME INSTABILITY CREDIT: IRB BARCELONA Researchers at IRB Barcelona identify critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches. The results have been published in Nature Communications....
Case Western Reserve University researchers combine novel chemical method with CRISPR gene-editing tools to target disease-specific versions of genetic code. The gene-editing technique known as CRISPR accelerated biological and medical research in the last decade by allowing scientists to repair the DNA of human cells almost as simple as using a pair of scissors. Gene-editing—and especially CRISPR,...
Defective mitochondria – the ‘batteries’ that power the cells of our bodies – could in future be repaired using gene-editing techniques. Scientists at the University of Cambridge have shown that it is possible to modify the mitochondrial genome in live mice, paving the way for new treatments for incurable mitochondrial disorders. Our cells contain mitochondria,...
