September 9, 2024 by Ecole Polytechnique Federale de Lausanne Credit: Pixabay/CC0 Public DomainEvery cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene regulation; essentially how and when genes are turned on...
September 3, 2024 by Gabriele Meseg-Rutzen, University of Cologne Representative gene–gene relationship changes with age, captured by pairwise correlation and a GRN-based approach. Credit: Nature Aging (2024). DOI: 10.1038/s43587-024-00696-yGene regulation in our cells—the decision on which proteins are produced for the various processes of the cell—is strictly regulated. It has long been assumed that this...
UNIVERSITY OF ROCHESTER IMAGE: IN COMPARING THE GENE EXPRESSION PATTERNS OF 26 SPECIES WITH DIVERSE LIFESPANS, UNIVERSITY OF ROCHESTER BIOLOGISTS FOUND THAT THE CHARACTERISTICS OF THE DIFFERENT GENES WERE CONTROLLED BY CIRCADIAN OR PLURIPOTENCY NETWORKS. CREDIT: UNIVERSITY OF ROCHESTER ILLUSTRATION / JULIA JOSHPE Natural selection has produced mammals that age at dramatically different rates. Take,...
by Keck School of Medicine of USC Credit: CC0 Public Domain Since they hit the market, e-cigarettes have been touted as a safe alternative to tobacco cigarettes for adult smokers. When research began to suggest otherwise, many questioned whether smoking was still to blame for adverse effects, since most vapers are either “dual users” who...
How cells develop and the diseases that arise when development goes wrong have been a decades-long research focus in the laboratory of Distinguished Professor of Biology Ellen Rothenberg. In particular, the lab studies the development of immune cells known as T cells, which act as “intelligence agents”—they circulate throughout the body, detect threats, and determine what kind of...
Scientists at the University of California, Irvine have developed a new deep-learning framework that predicts gene regulation at the single-cell level. Deep learning, a family of machine-learning methods based on artificial neural networks, has revolutionized applications such as image interpretation, natural language processing and autonomous driving. In a study published recently in Science Advances, UCI researchers describe how...
