Tag: <span>gene variants</span>

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Korean Genome Project data released for public use
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Korean Genome Project data released for public use

by Bob Yirka , Medical Xpress A team of researchers with members affiliated with a large number of institutions in Korea, two in the U.S. and one in the U.K. has released data from the initial phase of the Korean Genome Project (Korea1K). In their paper published in the journal Science Advances, the group notes...

Gene inactivation of PTEN drives cancer predisposition
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Gene inactivation of PTEN drives cancer predisposition

by Cleveland Clinic An international team of researchers co-led by Cleveland Clinic have identified why patients without PTEN mutations may still experience the high cancer risk associated with PTEN hamartoma tumor syndrome (PHTS). In a new study published in the New England Journal of Medicine, a research team co-led by Charis Eng, MD, Ph.D., Cleveland...

New genetic markers of type 2 diabetes identified in East Asians
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New genetic markers of type 2 diabetes identified in East Asians

In the largest study of its kind in any non-European population, an international team of researchers, including a University of Massachusetts Amherst genetic epidemiologist, has identified new genetic links with type 2 diabetes among 433,540 East Asian individuals. The findings, published in Nature, “provide additional insight into the biological basis of type 2 diabetes,” says...

The hidden links between mental disorders
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The hidden links between mental disorders

Psychiatrists have a dizzying array of diagnoses and not enough treatments. Hunting for the hidden biology underlying mental disorders could help. In 2018, psychiatrist Oleguer Plana-Ripoll was wrestling with a puzzling fact about mental disorders. He knew that many individuals have multiple conditions — anxiety and depression, say, or schizophrenia and bipolar disorder. He wanted...

Pharmacists warn against malarial drugs as a cure for coronavirus
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Pharmacists warn against malarial drugs as a cure for coronavirus

PHARMACY experts at the University of Huddersfield are urging caution over claims that widely-available antimalarial drugs could be a “magic bullet” to prevent and cure CoVid-19. And the medicines can – if used rashly – have serious side effects. Although there have been some encouraging signs from small-scale preliminary trials of the drugs chloroquine (CQ)...

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Highly prevalent gene variants in minority populations cause kidney disease

Preclinical study is first proof-of-concept to pave way for development of new therapeutics Representative images of kidney tissue from APOL1-G1 and APOL1-G2 mice, showing severe scarring of the kidney filter. African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants — named...

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