Yes, you can have a greater risk of high blood pressure because of your genes. But you can do something about it.Peer-Reviewed Publication NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY Certain genes associated with hypertension affect blood pressure from early in life, and they increase the risk of cardiovascular disease as you get older. However, you...
Tag: <span>Genes</span>
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Study discovers 103 genes that cause inherited diseases when mutated can also increase cancer risk
by The Spanish National Cancer Research Centre Systematic analysis of the enrichment of rare pathogenic variants in cases compared to control samples. a Proposed hypothesis that rare pathogenic variants in Mendelian disease-associated genes (OMIM genes) increase the risk of cancer. b Overview of the case–control analysis. Principal components analysis (PCA) using common variants was performed to...
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New roles for autophagy genes in cellular waste management and aging
Autophagy genes help extrude protein aggregates from neurons in the nematode C. elegans Peer-Reviewed Publication BUCK INSTITUTE FOR RESEARCH ON AGING Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and...
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A novel switch to turn genes on/off on cue, a promising step toward safer gene therapy
Peer-Reviewed Publication BAYLOR COLLEGE OF MEDICINE Just like a doctor adjusts the dose of a medication to the patient’s needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window. Staying within the therapeutic window is important...
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Early-life stress changes more genes in the brain than a head injury
by The Ohio State University Credit: Pixabay/CC0 Public Domain A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life. In an animal study, stress changed the activation level of many more genes in the brain than were changed by a...
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Scientists Spot Genes Linked to Raynaud’s Phenomenon
(Adobe Stock) Scientists have discovered two genes that may trigger Raynaud’s phenomenon, a condition that can cause fingers and toes to go cold and numb because of the constriction of tiny blood vessels under the skin. “We identify two distinct genes that point to two distinct mechanisms,” lead researcher Maik Pietzner, chair in health data...
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Genes linked to sex and age pave the way for tailored weight-loss drugs
By Bronwyn Thompson August 02, 2023 Sex-specific genetic therapy could make it easier for everybody to lose weight Depositphotos Obesity is a massive global crisis, with around 650 million adults and 124 million children and adolescents impacted. It’s also estimated that up to 70% of body size is directly linked to genetic factors. In addition...
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Researchers identify genes that can improve stroke diagnosis and treatment
by Claudia Coons, UC Davis Differential expression across time points. Differentially expressed genes (DEGs) across time points versus VRFC (0–24 h (TP1), 24–48 h (TP2), and >48 h (TP3)) in monocytes (A), neutrophils (B), and whole blood (C). Venn diagrams of the numbers of DEGs at each time point are shown on the left, and on...
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Genes responsible for coronary artery disease identified
by University of Virginia Credit: Circulation Research (2023). DOI: 10.1161/CIRCRESAHA.122.321586 University of Virginia researchers and their collaborators have identified genes that play key roles in the development of coronary artery disease. UVA’s findings essentially pick culprits responsible for coronary artery disease (CAD) out of a far, far larger lineup of potential genetic suspects. That gives scientists promising targets as they...
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Describing the genes associated with the sixth sense
by Anke Brodmerkel, Max Delbrück Center for Molecular Medicine Different populations of sensory neurons cell bodies in a dorsal root ganglion (right) and their axons in the spinal cord (left): The cells in green detect proprioceptive information while the cells in red thermal and tactile information. Credit: Stephan Dietrich, Zampieri Lab, Max Delbrück Center To perform...