RESEARCH ORGANIZATION OF INFORMATION AND SYSTEMS IMAGE: RESEARCH TEAM UPGRADED CLINICAL DECISION SUPPORT SYSTEM PUBCASEFINDER TO PROVIDE BETTER DIAGNOSIS WITH RARE/GENETIC DISEASE CREDIT: © 2022 FUJIWARA ET AL. HUMAN MUTATION PUBLISHED BY WILEY PERIODICALS LLC Even trained experts can spend hours looking for trusted medical sources (e.g., textbooks, literature, and databases) for candidate diseases to...
by Garvan Institute of Medical Research Dr Ira Deveson of the Garvan Institute of Medical Research. Credit: Garvan Institute of Medical Research A new DNA test, developed by researchers at the Garvan Institute of Medical Research in Sydney and collaborators from Australia, UK and Israel, has been shown to identify a range of hard-to-diagnose neurological...
UNIVERSITY OF CALIFORNIA – SAN DIEGO New research led by bioengineers at the University of California San Diego could make it much simpler to repair disease-causing mutations in RNA without compromising precision or efficiency. The new RNA editing technology holds promise as a gene therapy for treating genetic diseases. In a proof of concept, UC...
January 24, 2022 8.31am EST Author Deborah FullerProfessor of Microbiology, School of Medicine, University of Washington The two most successful coronavirus vaccines developed in the U.S. – the Pfizer and Moderna vaccines – are both mRNA vaccines. The idea of using genetic material to produce an immune response has opened up a world of research...
HARVARD UNIVERSITY IMAGE: POSTDOCTORAL FELLOW SAMAGYA BANSKOTA (LEFT) AND GRADUATE STUDENT ADITYA RAGURAM (RIGHT), CO-LEAD AUTHORS, INVESTIGATE IN VIVO DELIVERY OF THERAPEUTIC PROTEINS AT THE LIU LAB. CREDIT: JULIA MCCREARY/ HARVARD GRADUATE STUDENT. A team of researchers led by Harvard and Broad Institute scientists has developed a new drug delivery system using engineered DNA-free virus-like...
Genetic screening for prostate cancer in GP surgeries could be effective at picking up otherwise undiagnosed cases of the disease, a new pilot study shows. Researchers ‘barcoded’ men for their genetic risk of prostate cancer by testing each for 130 DNA changes – and gave those at higher risk follow-up checks. Their study found that...
by FAPESP Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, and another thousand are being studied to the same end. The diagnosis and treatment of the...
by Jane Tiller, The Conversation In the past week, news has spread of a Florida judge’s decision to grant a warrant allowing police to search one of the world’s largest online DNA databases, for leads in a criminal case. The warrant reportedly approved the search of open source genealogy database GEDMatch. An estimated 1.3 million...
The system allows researchers more control over DNA changes, potentially opening up conditions that have challenged gene-editors. Heidi Ledford For all the ease with which the wildly popular CRISPR–Cas9 gene-editing tool alters genomes, it’s still somewhat clunky and prone to errors and unintended effects. Now, a recently developed alternative offers greater control over genome edits — an advance...
By Lois Zoppi, BAReviewed by Kate Anderton, B.Sc. (Editor) The reason why a commonly used range of drugs is not effective in some patients living with Crohn’s disease has so far not been identified. However, a collaboration between the University of Exeter, Royal Devon & Exeter NHS Foundation Trust and the Wellcome Sanger Institute has discovered a genetic marker...
