KOBE UNIVERSITY IMAGE: A: Illustration of the experiment. Green fluorescent proteins were introduced so that the target gene and the entire neuron could be observed. B: Each target gene was separately introduced into the cerebral cortex and dendritic spine dynamics were tracked for a period of 2 days (on the 21st and 22nd days after...
by Weill Cornell Medical College Histone H1 (fragment shown here in gray) binds and condenses DNA to repress gene activity. Mutations in histone H1 (highlighted in red) have been identified at high frequency in many hematological malignancies. Credit: Weill Cornell Medical College Mutations in proteins called histone H1, which help package DNA in chromosomes, are a...
