by Jane E. Dee, Yale University Fig. 1: Reactivation of Pkd2 reverses cyst formation. Credit: DOI: 10.1038/s41588-021-00946-4 Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder, causes fluid-filled cysts to develop on the kidneys, which can impair their function. As part of the growth of cysts, the kidneys develop inflammation and fibrosis, or scarring. The disease...