ETH researchers have discovered that they can use light-sensitive molecules to switch genetic networks on and off as required. Their finding gives rise to an easy method for dynamically controlling biotechnological substance production. Tetracycline (Tc), an antibiotic, and its derivative anhydrotetracycline (aTc) enjoy widespread use in biotechnology and synthetic biology. Both molecules influence gene expression....
Tag: <span>Genetic</span>
Study shows highly reproducible sex differences in aspects of human brain anatomy
by National Institutes of Health A scientific analysis of more than 2,000 brain scans found evidence for highly reproducible sex differences in the volume of certain regions in the human brain. This pattern of sex-based differences in brain volume corresponds with patterns of sex-chromosome gene expression observed in postmortem samples from the brain’s cortex, suggesting...
Genetic malfunction of brain astrocytes triggers migraine
by University of Zurich Neuroscientists of the University of Zurich shed a new light on the mechanisms responsible for familial migraine: They show that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence. Migraine is one of the most disabling disorders, affecting one in seven people and...
Skin cancer: men are genetically more prone
As COVID-19 restrictions loosen this summer, Canadians will spend more time outdoors and make the most of the sunshine. A new study from McGill University suggests why men may be more genetically prone to develop skin cancer. The research led by Professor Ian Watson of McGill’s Goodman Cancer Research Centre (GCRC), published in the journal...
Researchers say genetics may determine wound infection and healing
A recent study led by Texas Tech’s Department of Biological Sciences and Natural Science Research Laboratory determined that certain genes are associated with the pathogens that infect chronic wounds and hinder the healing process. CALEB PHILLIPS; ASSISTANT PROFESSOR OF BIOLOGICAL SCIENCES AND DIRECTOR OF THE PHILLIPS LABORATORY, COLLEGE OF ARTS & SCIENCES; CURATOR OF GENETIC...
Genetic diversity facilitates cancer therapy
by Max Planck Society The constant battle against infectious pathogens has had a decisive influence on the human immune system over the course of our evolution. A key role in our adaptation to pathogens is played by HLA molecules. These proteins activate the immune system by presenting it with fragments of pathogens that have entered...
Scientists tackle potential drug resistance by using new single-cell genetic method
UNIVERSITY OF NOTRE DAME Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor’s potential resistance to a drug, and then identified a drug combination that reversed that resistance. Siyuan Zhang, the Dee Associate Professor of Biological Sciences at Notre Dame, and his...
Exploring genetic “dark matter,” researchers gain new insights into autism and stroke
Posted Today With its elegant double helix and voluminous genetic script, DNA has become the of darling of nucleic acids. Yet, it is not all powerful. In order for DNA to realize its potential—for genes to become proteins—it must first be transcribed into RNA, a delicate molecule that requires intense care and guidance. “Gene expression is a lot more complicated...
Genetic study reveals metabolic origins of anorexia
by King’s College London A global study, led by researchers at King’s College London and University of North Carolina at Chapel Hill, suggests that anorexia nervosa is at least partly a metabolic disorder, and not purely psychiatric as previously thought. The research was published in Nature Genetics today. The large-scale genome-wide association study, undertaken by over 100 academics worldwide, identified eight genetic variants...
New study discovers genetic changes linked to leukaemia in children with Down’s syndrome
Posted Today This news or article is intended for readers with certain scientific or professional knowledge in the field. Researchers at the University of Oxford, in collaboration with colleagues from Hannover Medical School and Martin-Luther-University Halle-Wittenberg, have discovered the specific gene mutations that are required for the development of leukaemia in children with Down’s syndrome. Children...