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Genetically engineered cell therapies with mRNA lipid nanoparticles for transferrable platelets
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Genetically engineered cell therapies with mRNA lipid nanoparticles for transferrable platelets

by Thamarasee Jeewandara , Phys.org Platelets transfected with mRNA using LNP can express exogenous protein. (A) Schematic describing the transfection of platelets using mRNA-LNP. (B) NanoLuc expression, measured as the relative luminescence units (RLU) per total protein, using various transfection agents (n = 3). (C and D) Representative flow cytometry plots and quantification of median...