Soybean oil linked to metabolic and neurological changes in mice UNIVERSITY OF CALIFORNIA – RIVERSIDE New UC Riverside research shows soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer’s disease, anxiety, and depression. Used for fast food frying, added to packaged foods, and fed to livestock,...
Tag: <span>Genetics</span>
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Gene Delivery Device to Make Engineered Cell Therapies Much Cheaper
The technology, called deterministic mechanoporation (DMP), consists of a microfluidic device that allows large numbers of living cells to be injected with genetic materials. Unlike the biochemical approaches that are typically used, the new approach is mechanical. Using fluid flow, cells are dragged toward microscopic needles within the device. The cells are pierced and immediately...
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Genetics may determine who benefits from broccoli’s effects on kidney health
by American Society of Nephrology New research indicates that the benefits of a dietary compound on kidney health may depend on an individual’s genetics. The findings, which appear in an upcoming issue of JASN, may be helpful for tailoring interventions to prevent or treat kidney disease. Glutathione S-transferase mu-1 (GSTM1) is an enzyme that plays...
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Researchers find link between eye disease and degeneration of the brain
by Agency for Science, Technology and Research (A*STAR), Singapore A global research team led by scientists from Singapore and the United States has discovered new evidence that there is an underlying link between degeneration of the eye and brain. They found that genetic variation at a beta-amyloid gene was significantly associated with increased risk of...
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Potential genetic markers of multiple sclerosis severity
JOHNS HOPKINS MEDICINE In a bid to determine factors linked to the most debilitating forms of multiple sclerosis (MS), Johns Hopkins Medicine researchers say they have identified three so-called “complement system” genes that appear to play a role in MS-caused vision loss. The researchers were able to single out these genes — known to be...
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Exploring an unsung part of the brain: the choroid plexus
by Stephen Lyons, Children’s Hospital Boston If you’ve never heard of the choroid plexus, you’re not alone. In fact, few neuroscientists know much about this part of the brain. In the words of the late comedian Rodney Dangerfield, the choroid plexus “don’t get no respect.” But that’s beginning to change, thanks in part to Maria Lehtinen, Ph.D., who has made the choroid plexus the focus of her research....
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New universe of miniproteins is upending cell biology and genetics
By Mitch LeslieOct. 17, 2019 , 2:00 PM Mice put human runners to shame. Despite taking puny strides, the rodents can log 10 kilometers or more per night on an exercise wheel. But the mice that muscle biologist Eric Olson of the University of Texas Southwestern Medical Center in Dallas and colleagues unveiled in 2015...
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Inflammation amps up neurite growth, gene expression involved in heat, cold sensitivity
by Tracey Peake, North Carolina State University Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal—but not physical- sensations in mice. The work sheds light on the role that inflammation-induced over expression of calcium channel genes may play in...
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Genetic markers linked to the start of symptoms of Parkinson’s disease
by University of Barcelona Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro), Hospital Clínic and the IDIBAPS have identified a group of genetic variants related to the starting point of Parkinson’s disease Credit: University of Barcelona – UBNeuro Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro), Hospital...
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Genetic markers linked to the start of symptoms of Parkinson’s disease
by University of Barcelona Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro), Hospital Clínic and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) have identified a group of genetic variants related to the starting point of Parkinson’s disease. These results, published in the journal Movement Disorders, will enable delimiting the research on new therapeutic targets, and...