Tag: <span>Genetics</span>

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Researchers Identify Novel Genetic Variants Linked to Type-2 Diabetes
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Researchers Identify Novel Genetic Variants Linked to Type-2 Diabetes

After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration’s (VHA) Corporal Michael J. Crescenz Veterans Affairs Medical Center (CMCVAMC) found hundreds of genetic variants never before linked to the disease....

Biomarker test highly accurate in detecting early kidney cancer
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Biomarker test highly accurate in detecting early kidney cancer

by Dana-Farber Cancer Institute A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists, say scientists from Dana-Farber Cancer Institute. The report in Nature Medicine suggests that if validated in larger trials and applied widely, the non-invasive...

Blood cell mutations linked to leukemias are inevitable as we age
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Blood cell mutations linked to leukemias are inevitable as we age

by RIKEN A new study by researchers at the RIKEN Center for Integrative Medical Science in Japan reports differences in blood cell mutations between Japanese and European populations. The study found that these pre-clinical mutations were strongly associated with different types of cancers and can explain why Europeans have higher rates of chronic lymphocytic leukemia,...

Genomes front and center of rare disease diagnosis
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Genomes front and center of rare disease diagnosis

by National Institute for Health Research BioResource A research program pioneering the use of whole-genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease. Whole genome sequencing is the technology used by the 100,000 Genomes Project, a service set up by the government which aims to introduce routine...

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Skin cancer: men are genetically more prone

As COVID-19 restrictions loosen this summer, Canadians will spend more time outdoors and make the most of the sunshine. A new study from McGill University suggests why men may be more genetically prone to develop skin cancer. The research led by Professor Ian Watson of McGill’s Goodman Cancer Research Centre (GCRC), published in the journal...

How ApoE4 endangers the brain
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How ApoE4 endangers the brain

by Max Delbrück Center for Molecular Medicine Apolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients, including with polyunsaturated fatty acids—which are building blocks of the membranes surrounding the neurons. In addition, certain unsaturated fatty acids are converted into so-called endocannabinoids. These are endogenous...

Researchers say genetics may determine wound infection and healing
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Researchers say genetics may determine wound infection and healing

A recent study led by Texas Tech’s Department of Biological Sciences and Natural Science Research Laboratory determined that certain genes are associated with the pathogens that infect chronic wounds and hinder the healing process. CALEB PHILLIPS; ASSISTANT PROFESSOR OF BIOLOGICAL SCIENCES AND DIRECTOR OF THE PHILLIPS LABORATORY, COLLEGE OF ARTS & SCIENCES; CURATOR OF GENETIC...

Computer algorithms find tumors’ molecular weak spots
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Computer algorithms find tumors’ molecular weak spots

By Roxanne KhamsiJun. 11, 2020 , 2:00 PM In 2016, doctors invited Eileen Kapotes to join a clinical trial for a drug that had never been used for her disease. Kapotes, a first grade teacher in her 50s, was fighting an aggressive breast cancer that had spread through her body. She had endured grueling treatments...

Convenient spit test helps women assess cancer risk from the comfort of their own homes
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Convenient spit test helps women assess cancer risk from the comfort of their own homes

First-of-its-kind clinical trial validates remote genetic counseling STAND UP TO CANCER STAND UP TO CANCER, OVARIAN CANCER RESEARCH ALLIANCE, NATIONAL OVARIAN CANCER COALITION LOGOS view more CREDIT: STAND UP TO CANCER, OVARIAN CANCER RESEARCH ALLIANCE, NATIONAL OVARIAN CANCER COALITION (New York) June 01, 2020 – Genetic testing for cancer risk can significantly improve the prevention...

Tuberculosis vaccine strengthens immune system
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Tuberculosis vaccine strengthens immune system

by University of Bonn A tuberculosis vaccine developed 100 years ago also makes vaccinated persons less susceptible to other infections. While this effect has been recognized for a long time, it is not known what causes it. Together with colleagues from Australia and Denmark, researchers from Radboud university medical center the universities of Nijmegen and...