An algorithm that can analyse hundreds of millions of genetic sequences has identified DNA-cutting genes and enzymes that are extremely rare in nature. Sara Reardon A computer generated molecular structure of the CRISPR–Cas9 protein using a guide RNA sequence to cut DNA. The CRISPR–Cas9 system (pictured) is used to find and cut specific DNA sequences.Credit:...
by Bar-Ilan University Credit: Pixabay/CC0 Public DomainSevere combined immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts. Left untreated, SCID proves fatal within the first year of life. The conventional treatment for SCID patients...
by University of Tsukuba Credit: pogonici/Shutterstock Hematopoietic stem cells (HSCs) are rare cells found in the bone marrow that produce red blood cells, white blood cells, and platelets. Their correct functioning is indispensable for the growth and health of an organism. Accordingly, defects in the DNA of hematopoietic stem cells (mutations) can cause impaired blood production...
LA JOLLA, CA – Over the past decade we’ve learned that billions of people carry a mysterious specter in their DNA that strongly increases their risk for life threatening cardiovascular diseases, such as heart attacks, aneurysms or strokes, no matter what diet, exercise or medical regimen they follow. IMAGE: MICROSCOPY IMAGE SHOWING VASCULAR SMOOTH MUSCULAR...
