by Keck School of Medicine Biologically important changes in DNA seen in smokers are also being found in people who vape, according to a new study published in the journal Epigenetics. A team of scientists at the Keck School of Medicine of USC have found people who vape exhibit similar chemical modifications in their overall...
Researchers led by a team from Osaka University find a link between the gut microbiome, the host genome, and rheumatoid arthritis in Japanese patients OSAKA UNIVERSITY Osaka, Japan – One of the most astounding discoveries of recent times is just how much influence gut bacteria have on our health and well-being. In addition to extracting...
The ultimate goal of genome editing is to be able to make any specific change to the blueprint of life. A ‘search-and-replace’ method for genome editing takes us a giant leap closer to this ambitious goal. Randall J. Platt Variation in the DNA sequences that constitute the blueprint of life is essential to the fitness...
“WE WILL GIVE EVERY CHILD THE BEST POSSIBLE START IN LIFE BY ENSURING THEY GET THE BEST POSSIBLE MEDICAL CARE AS SOON AS THEY ENTER THE WORLD.” BY DAN ROBITZSKI / AN HOUR AGO The U.K. may start offering full genome sequencing to every child born in the country, an official says. Health Secretary Matt...
This news or article is intended for readers with certain scientific or professional knowledge in the field. University of Tokyo researchers and their collaborators have demonstrated that a special structure that forms when DNA is damaged helps to restore it. Human cells have a mechanism for recognizing this structure, consisting of DNA and RNA, which promotes accurate...
A weighty new study shows that CRISPR therapies can cut fat without cutting DNA. In a paper published Dec. 13, 2018, in the journal Science, UC San Francisco researchers describe how a modified version of CRISPR was used to ramp up the activity of certain genes and prevent severe obesity in mice with genetic mutations that...
More than half of adults in the Western hemisphere over the age of 40 have small bulging pouches inside their intestine known as diverticula. Caused by a weakening of the outer lining of the intestine, these pouches are typically harmless. Credit: CC0 Public Domain But for some, these pouches can become painfully inflamed or infected,...
A new approach that distills deluges of genetic data and patient health records has identified a set of telltale patterns that can predict a person’s risk for a common, and often fatal, cardiovascular disease, according to a new study from the Stanford University School of Medicine. This graphical abstract illustrates how a machine-learning approach integrating...
It has been almost 20 years since the human genome was first sequenced, but researchers still know little about how the genome is folded up and organized within cells. In a paper to be published August 28 in the Journal of Cell Biology, researchers from the University of Illinois at Urbana-Champaign describe a new technique...
Researchers at UMass Medical School have developed a genome-editing strategy to correct disease-causing DNA mutations in mouse models of human genetic diseases, according to research published in the Aug. 18 edition of Nature Biotechnology. Credit: CC0 Public Domain First author Dan Wang, Ph.D., instructor in microbiology & physiological systems, together with co-corresponding authors Guangping Gao, Ph.D., the Penelope Booth...
