By Dr. Liji Thomas, MD The current COVID-19 pandemic demonstrates the vast unknown of virology, which continues to challenge the ability of humanity to remain healthy when faced with pathogens. While most known microbes have restricted affinity for specific species, continuing to adapt with the host species, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
by National Institute for Health Research BioResource A research program pioneering the use of whole-genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease. Whole genome sequencing is the technology used by the 100,000 Genomes Project, a service set up by the government which aims to introduce routine...
by University of California – San Diego Most traditional cancer therapies target either the tumor cells themselves or indiscriminately kill any rapidly dividing cell. New findings by researchers at University of California San Diego School of Medicine indicate that manipulating macrophages, a type of immune cell found abundantly in the tissues surrounding a tumor, could...
Durham, NC – A new study released today in STEM CELLS addresses a significant problem that has been confronting human mesenchymal stem cells (hMSCs) therapy. While hundreds of clinical trials involving thousands of patients are under way to test hMSCs’ ability to treat everything from heart disease to brain injury, there has been no way...
by Jake Miller, Harvard Medical School A team of researchers from Harvard Medical School, Brigham and Women’s Hospital, Socios En Salud, and the Broad Institute at Harvard and MIT report they have identified the single largest genetic contributor to height known to date. The findings, published May 13 in Nature, are based on an analysis...
by Babraham Institute A study led by researchers at the Babraham Institute in collaboration with the Wellcome Sanger Institute has uncovered how variations in a non-protein coding ‘dark matter’ region of the genome could make patients susceptible to complex autoimmune and allergic diseases such as inflammatory bowel disease. The study in mice and human cells...
CHAMPAIGN, Ill. — In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells. In a new study published in the journal ACS Nano, researchers at the University of Illinois at Urbana-Champaign demonstrated that “nanostimulators” – nanoparticles...
by IOS Press Overview of the currently included countries in the IPDGC and IPDGC-affiliated efforts. IPDGC = International Parkinson Disease Genomics Consortium, LARGE-PD = Latin American Research Consortium on the Genetics of Parkinson Disease, Lux GIANT = Luxembourg-German-Indian Alliance on Neurodegenerative diseases and Therapeutics. Credit: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of...
by SWOG Cancer Research Network A majority of cancer patients don’t understand key aspects of the genomic test results they receive as participants in biomarker-driven clinical trials, according to a first-of-its-kind pilot study conducted under the Lung Cancer Master Protocol (Lung-MAP). In a September 9 presentation at the World Conference on Lung Cancer in Barcelona,...
In an important step toward eradicating tuberculosis (TB), the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has signed a licensing agreement with an international biomedical firm, Advanced Biological Laboratories (ABL), to market and distribute TGen’s patented Next Generation Sequencing based TB test technology. For now, the test—called DeepChek-TB—is available for research...
