Senolytic drugs that destroy senescent cells, and later on, other senotherapies that either prevent senescence or block the senescence-associated secretory phenotype (SASP), are going to be very important in the treatment of aging. Senescent cells accumulate with age and are highly damaging to tissues. Via the SASP, even comparatively small numbers of lingering senescent cells...
Research in the Journal of Leukocyte Biology suggests increased α5β1 integrin can improve tumor-killing behavior by CAR-T therapy in the aging population A new report in the Journal of Leukocyte Biology describes an important step toward developing cancer treatments involving the body’s immune system. Specifically, chimeric antigen receptor T cell (CAR-T) therapy involves collecting white blood cells...
