by Medical College of Georgia at Augusta University Credit: CC0 Public Domain Inhaled CBD shrinks the size of the highly aggressive, lethal brain tumor glioblastoma in an animal model by reducing the essential support of its microenvironment, researchers report. “We saw a significant reduction in the size of the tumor and its microenvironment was different,”...
by Cleveland Clinic Glioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0 New Cleveland Clinic research has found that drugs originally designed to help treat Alzheimer’s disease may hold promise for glioblastoma, the most common and lethal type of primary brain tumor. The findings were published in Nature Cancer. A class of drugs called BACE1 inhibitors were once among...
Donald M. O’Rourke, MD, director of the Glioblastoma Translational Center of Excellence at Penn Medicine, feels energized. After a lot of frustration and too few successes, the cell therapy field has reached a new phase in its pursuit for better treatments for the deadly brain cancer glioblastoma multiforme (GBM). For decades, treatment approaches using surgery,...
by Innovation Center of NanoMedicine Glucose-PEGylated avelumab prevented the growth of glioblastoma. Credit: 2021 Innovation Center of NanoMedicine Multi-institutional researchers have succeeded in efficiently delivering an immune checkpoint inhibitor (ICI) into the mouse brain, confirming its high efficacy and specificity in treating orthotopically transplanted mice with glioblastoma (GBM). The research was published in Nature Biomedical Engineering....
by Cancer Biology and Medicine Credit: CC0 Public Domain Gliomas are the most common primary brain tumors in adults. Among them, the high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease rapidly progresses to an advanced stage in a short span of time,...
Glioblastoma is the most lethal and malignant adult brain cancer that may arise from neuroglial stem or progenitor cells. Certain gene mutations or those with a known history of other cancers and radiation therapy may predispose patients to develop brain cancer. Tumour relapse is invariably inevitable due to the resistance of glioblastoma towards standard therapies....
by McGill University Credit: Unsplash/CC0 Public Domain McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy. Due to its resistance to therapy, glioblastoma is the most common and aggressive cancerous brain tumor in adults. It grows...
by Houston Methodist Device helmet with 3 on oscillators securely attached. The oscillators are connected to a controller box powered by a rechargeable battery. Credit: Houston Methodist Houston Methodist Neurological Institute researchers from the department of neurosurgery shrunk a deadly glioblastoma tumor by more than a third using a helmet generating a noninvasive oscillating magnetic field that the...
BOSTON COLLEGE Chestnut Hill, Mass. (6/10/2021) – A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body’s own metabolism to fight this particularly...
by Melissa Rohman, Northwestern University Gliobastoma (astrocytoma) WHO grade IV – MRI coronal view, post contrast. 15 year old boy. Credit: Christaras A/ Wikipedia. Inhibiting a novel protein variant within glioma stem cells may be a promising therapeutic approach to treat glioblastoma, according to a Northwestern Medicine study published in Nature Cell Biology. “With this study, we...
