by Northwestern University An early clinical trial in individuals with the deadly brain cancer, glioblastoma, showed an experimental spherical nucleic acid (SNA) drug developed by Northwestern University scientists was able to penetrate the blood-brain barrier and trigger the death of tumor cells. This is the first time a nanotherapeutic has been shown to cross the blood-brain...
by Children’s National Hospital A mouse model of glioblastoma, an aggressive type of cancer that can occur in the brain, suggests that this recalcitrant cancer originates from a pool of stem cells that can be a significant distance away from the resulting tumors. The findings of a new study, led by Children’s National Hospital researchers...
UNIVERSITY OF VIRGINIA HEALTH SYSTEM THE DISCOVERY OF THE ONCOGENE RESPONSIBLE FOR GLIOBLASTOMA COULD BE THE BRAIN TUMOR’S ACHILLES’ HEEL, SAYS HUI LI, PHD, OF THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE AND THE UVA… view more CREDIT: UVA HEALTH Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor....
by Uppsala University Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The study is published in Genome Biology. The human genome consists of nearly 22,000 genes. Many studies have explored the nearly...
By Nick Lavars May 26, 2020 As the most aggressive type of brain cancer and one with a very poor survival rate, there is a desperate need for new and improved treatments for glioblastoma. Scientists at Virginia Commonwealth University may have uncovered a powerful new tool in this regard, in the form of an already...
Bethesda, MD – Findings from a new study examining human and canine brain cancer cells suggest that cannabidiol could be a useful therapy for a difficult-to-treat brain cancer. Cannabidiol, or CBD, is a non-psychoactive chemical compound derived from marijuana. The study looked at glioblastoma, an often-deadly form of brain cancer that grows and spreads very...
by Dorian Martin, Texas A&M University A team led by Texas A&M University’s College of Veterinary Medicine & Biomedical Sciences’ (CVM) researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer. The Texas A&M team’s research focuses on the AH...
Large randomized clinical trials can uncover biomarkers that indicate which cancer treatments are likely to work best for individual patients. But it’s been challenging to find these biomarkers in rarer cancers where such robust data aren’t available. Using a new approach that combines data from human tumors grown in mice with data from The Cancer Genome Atlas, a team led...
NEW YORK (GenomeWeb) – A team led by researchers at Washington University has identified molecular features that differ between glioblastoma (GBM) brain tumors of males and females and may be used to better tailor treatment. As they reported online yesterday in Science Translational Medicine, the researchers used available transcriptome data from the Cancer Genome Atlas...
Scientists at the Virginia Tech Carilion Research Institute have solved a 125-year-old mystery of the brain, and, in the process, uncovered a potential treatment for acquired epilepsy. Since 1893, scientists have known about enigmatic structures called perineuronal nets wrapped around neurons, but the function of the nets remained elusive. IMAGE: A RESEARCH TEAM LED BY HARALD SONTHEIMER...
