SALK INSTITUTE IMAGE: CAPTION: FROM LEFT: IPSC-DERIVED DENTATE GYRUS (DG)-LIKE NEURONS (GREEN) FROM CONTROL SUBJECT; BIPOLAR LITHIUM RESPONDER; AND BIPOLAR LITHIUM NONRESPONDER. WHILE THE PERCENTAGE OF DG-LIKE NEURONS IS THE SAME FOR CONTROL AND BIPOLAR,THE GENE ACTIVATION PROFILES ARE DIFFERENT AND THE NONRESPONDER HAS LOW LEVELS OF LEF1. CREDIT: SALK INSTITUTE LA JOLLA–(January 5, 2021)...
