by Mikayla Mace Kelley, University of Arizona cSNX1.3 competitively inhibits binding of EGFR to SNX1. A Ribbon drawing of EGFR kinase domain (PDB ID 5CNO) and SNX1 Bar domain (PDB ID 4FZS). The proposed SNX1 binding site is well away from the kinase active site. B SDS page gels for purified SNX1 Bar domain (residues 301–522) and EGFR kinase...
