September 30, 2024 by University of Pittsburgh Microparticles containing the immune-modulating compound CCL2. Credit: Julie Kobyra, University of PittsburghTargeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research from the University of Pittsburgh. The study, published in Proceedings of the National Academy...
Tag: <span>Gum disease</span>
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Research reveals that intensive treatment for diabetes can reduces gum disease inflammation
September 17, 2024 by Osaka University Credit: Moe InoueWhile the link between diabetes and periodontal disease is known, the impact of diabetes treatment on periodontal health is less well understood. Research published in Diabetes, Obesity and Metabolism demonstrates that periodontal inflammation can be positively affected just by receiving intensive diabetes treatment. It is widely believed...
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How gum disease aggravates chronic obstructive pulmonary disease
by American Society for Microbiology Credit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how the connection plays out in the immune system remains unclear. This week in mSystems, a new study identifies immune system cells that play a critical role in...
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Special mouth rinse and brushes can help treat gum disease among diabetes patients
by Laurie Kaiser, University at Buffalo Credit: George Becker from Pexels Individuals with type 2 diabetes being treated for periodontitis may benefit from using an antimicrobial mouth rinse and small brushes to clean between teeth as part of their at-home oral care routine. This was a key finding in a recent study conducted by Patricia Diaz,...
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New study links gum disease to buildup of Alzheimer’s plaque formation
by Forsyth Institute Alveolar bone resorption and mRNA expression levels of RANKL and OPG in periodontal tissues of mice with ligature-induced experimental periodontal disease. A) In vivo experimental design (n = 36, 7–8 mice per group). The baseline group was left untreated, and four groups had ligatures around maxillary right and left second molars for different timepoints corresponding...
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Gum disease may lie at the root of some arthritis flareups
by Rockefeller University Blood vessels in the soft tissue between joints, during a rheumatoid arthritis flare-up. Credit: Laboratory of Molecular Neuro-oncology at The Rockefeller University It’s a well-documented medical mystery: Patients with gum disease are less likely to respond to rheumatoid arthritis treatments. But new research may help explain this link between gum disease and an otherwise disparate...
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Study suggests causative pathway between gum disease and rheumatoid arthritis
by Justin Jackson, Medical Xpress Oral mucosal breaks trigger systemic inflammatory responses.(A) Experimental workflow. (B) Inferred relative bacterial abundances from eight HMP body sites (n = 336). (C) Body site–inferred relative abundances for time points from RA patients with and without periodontal disease, median. (D) Inferred relative oral abundances in blood for one RA donor with and...
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New device for early detection of gum disease
by University of Birmingham Change in area under the curve (AUC) for all combinations of validated analytes for differentiating between health or gingivitis and periodontitis (HG vs. P), health and gingivitis (H vs. G), and mild and advanced periodontitis (MP vs. AP). Data are represented as truncated violin plots; solid lines represent median and dashed...
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Researchers developing topical gel that fights gum disease
A new gel may be able to relieve and treat symptoms of gum disease. Anna Efetova/Getty Images Almost half of all adults ages 30 or older have gum disease. Researchers from the NYU College of Dentistry have developed a topical gel to help treat and prevent periodontal (gum) disease. In experiments in mice, the gel...
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Gel treats gum disease by fighting inflammation
by New York University A topical gel that blocks the receptor for a metabolic byproduct called succinate treats gum disease by suppressing inflammation and changing the makeup of bacteria in the mouth. Credit: Yuqi Guo A topical gel that blocks the receptor for a metabolic byproduct called succinate treats gum disease by suppressing inflammation and...