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Microbiome study: Gum disease-causing bacteria borrow growth molecules from neighbors to thrive
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Microbiome study: Gum disease-causing bacteria borrow growth molecules from neighbors to thrive

by Marcene Robinson,  University at Buffalo Credit: CC0 Public Domain The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new University...

Microbiome study: Gum disease-causing bacteria borrow growth molecules from neighbors to thrive
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Microbiome study: Gum disease-causing bacteria borrow growth molecules from neighbors to thrive

The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new University at Buffalo-led study. The human body is filled with...

Researchers discover mechanism linking gum disease to heart disease, other conditions
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Researchers discover mechanism linking gum disease to heart disease, other conditions

Researchers at the University of Toronto have found evidence that neutrophil immune cell activity is the missing link connecting periodontal disease with heart disease, cancer and other inflammatory conditions – possibly including COVID-19. The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind the association...

Mechanism linking gum disease to heart disease, other inflammatory conditions discovered
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Mechanism linking gum disease to heart disease, other inflammatory conditions discovered

UNIVERSITY OF TORONTO – FACULTY OF DENTISTRY IMAGE: NEUTROPHIL ACTIVATION IS NOW BELIEVED TO BE AT THE ROOT OF OVERACTIVE INFLAMMATORY RESPONSES, AND LINKS CONDITIONS SUCH AS PERIODONTAL DISEASE AND HEART DISEASE. (TORONTO, ON) Oct. 20, 2020 — The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has...

The building blocks of gum disease
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The building blocks of gum disease

OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY (OIST) GRADUATE UNIVERSITY Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What’s more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even...

Gum disease, inflammation, hardened arteries may be linked to stroke risk
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Gum disease, inflammation, hardened arteries may be linked to stroke risk

by American Heart Association Gum disease was associated with a higher rate of strokes caused by hardening of large arteries in the brain and also with severe artery blockages that haven’t yet caused symptoms, according to preliminary research to be presented at the American Stroke Association’s International Stroke Conference 2020—Feb. 19-21 in Los Angeles, a...

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New study explores the link between obesity and gum disease

CWRU School of Dental Medicine research suggests treating one may impact the other CASE WESTERN RESERVE UNIVERSITY Obesity and gum (periodontal) disease are among the most common non-communicable diseases in the United States–and studies show these chronic conditions may be related. This new study explores the effect of obesity on non-surgical periodontal care and evaluates...

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Sentinels in the mouth

Special sensory cells in the gums protect against periodontitis MONELL CHEMICAL SENSES CENTER PHILADELPHIA (October 3, 2019) – Newly discovered chemical-sensing cells in the gums protect the mouth by standing guard against infections that damage soft tissue and destroy the bone that supports the teeth, report researchers from the Monell Chemical Senses Center in an animal study...

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Alzheimer’s drug trial targets by-product of gum disease

by  Alzheimer’s Research UK The pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer’s drug that targets toxic substances released by P. gingivalis, a bacteria linked to gum disease. In a poster presented at the Alzheimer’s Association International Conference today (Wednesday, July 17), researchers provided an overview of the development of the drug, known as COR388, and how they are working to test its ability to slow the progression...