by Sharita Forrest, University of Illinois at Urbana-Champaign Animal characteristics of conventionally raised C57BL/6J mice that underwent either ovariectomy (OVX) or sham (SHM) surgery and fed either a low-fat (LFD) or a high-fat diet (HFD). Final body weight (a) and energy intake (b) at the end of the 12-week study period as well as body weight...
by Delthia Ricks , Medical Xpress Teplizumab delays type 1 diabetes (T1D) in at-risk individuals in TN10 trial, but participants respond differently to the treatment. Systemic, non-pathogenic antibody responses to gut bacteria can be quantified by anti-commensal antibody (ACAb) assay. Individuals with higher IgG2 responses to specific gut bacteria are more likely to get early...
by Physicians Committee for Responsible Medicine Graphical Abstract. Credit: Complementary Therapies in Medicine (2023). DOI: 10.1016/j.ctim.2023.103002 A low-fat vegan diet that includes soy fosters changes in the gut microbiome that decrease postmenopausal vasomotor symptoms, or hot flashes, overall by 95%, according to a new study by the Physicians Committee for Responsible Medicine. A vegan diet...
by Molly Chiu, Baylor College of Medicine Plasma metabolites in historic controls versus recipients of RPS. a, UMAP ordination of median-centered plasma metabolite levels revealed four distinct clusters of metabolites. b, UMAP ordination stratified according to clinical group (historic controls in blue or recipients of RPS in orange), with the largest divergence in overlap at engraftment....
By Paul McClure August 03, 2023 A study has found a link between the gut microbiome and cocaine use, including the cravings that come following withdrawal Depositphotos A new study has provided the first evidence of a link between the gut microbiome and cocaine use and the cravings that follow withdrawal. The findings open the...
by Bob Yirka, Medical Xpress Example features and the species encoding the enzymes and pathways involved in the differential encoding of vitamin B processing in inflammatory arthritis. (A) Shown are examples of the most differentially encoded B vitamin pathways and enzymes. (B) Shown are the taxa contributing to vitamin B7 encoding. Credit: Science Translational Medicine (2023). DOI:...
by Liz Murphy, Massachusetts General Hospital Graphical abstract. Credit: Cell Host & Microbe (2023). DOI: 10.1016/j.chom.2023.04.007 A new study by investigators from Mass General Brigham has linked certain types of gut bacteria to the development of precancerous colon polyps. Their results are published in Cell Host & Microbe. “Researchers have done a lot of work to understand the relationship between...
by Digestive Disease Week Credit: Pixabay/CC0 Public Domain The balance of microbes in the human gut varies substantially from morning to night and even more by season—with profound fluctuations completely transforming the microbiome from summer to winter, according to a study to be presented at Digestive Disease Week (DDW) 2023. The microbiome—bacteria that live in...
Batya Swift Yasgur, MA, LSW April 25, 2023 Major depressive disorder (MDD) is linked to disruptions in energy and lipid metabolism, possibly caused by the interplay of the gut microbiome and blood metabolome, new research suggests. Investigators found that MDD had specific metabolic “signatures” consisting of 124 metabolites that spanned energy and lipid pathways, with some involving the tricarboxylic...
by Justin Jackson, Medical Xpress Graphical abstract of the study workflow and findings. Credit: Nature Microbiology (2023). DOI: 10.1038/s41564-023-01355-5 Published in Nature Microbiology, a study by researchers at the University of Copenhagen in Denmark has delved into the microbiota of patients with anorexia nervosa (AN) pathology and identifies the mechanistic interplay between restricted eating habits and how the gut microbiota’s...
