By Dr. Liji Thomas, MD The millions of bacteria residing in the gut play a very important role in health and in disease. However, a constant issue has been the lack of understanding of the actual composition of the healthy human gut microbiome. Now, a group of scientists have come up with a new method for...
Tag: <span>Gut microbiota</span>
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‘Bugs’ in the gut might predict dementia in the brain
DALLAS, Jan. 30, 2019 — The makeup of bacteria and other microbes in the gut may have a direct association with dementia risk, according to preliminary research to be presented in Honolulu at the American Stroke Association’s International Stroke Conference 2019, a world premier meeting for researchers and clinicians dedicated to the science and treatment...
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Small metabolites have big effects on the intestinal immune response
Gut microbiota such as lactobacillus produce lactate and pyruvate. These metabolites stimulate intestinal macrophages through the receptor GPR31, allowing macrophages to protrude trans-epithelial dendrites and take up pathogenic bacteria efficiently in the intestine. Accordingly, lactate and pyruvate cause enhanced immune responses to pathogenic bacteria and increased resistance to the infection. Credit: Osaka University For at...