by University of Surrey A representative scheme for the formulation development. Credit: International Journal of Pharmaceutics (2024). DOI: 10.1016/j.ijpharm.2024.123875Nano micelles of Retinol, a type of vitamin A commonly used in anti-aging beauty products, can also help wounds heal faster by promoting skin tissue regeneration, according to studies conducted by the University of Surrey and Phytoceutical Ltd.Their...
by TranSpread Hypoxia facilitates exosome production and release from BMSCs. (a) Transmission electron microscopy (TEM) revealed the morphology of noBMSC-Exos and hyBMSC-Exos (scale bar: 100 nm). (b) The size distribution of noBMSC-Exos and hyBMSC-Exos was examined using nanoparticle tracking analysis (NTA). (c and d) Western blotting analysis for exosome surface marker proteins, including CD9, CD63,...
by National University of Singapore A bandage pre-loaded with magnetic hydrogel is placed on the wound and an external device is used to accelerate the wound healing process. Credit: National University of SingaporeDiabetic patients whose natural wound-healing capabilities are compromised often develop chronic wounds that are slow to heal. Such non-healing wounds could cause serious infections...
by National Institutes of Health The piezoelectric wafer at left shows the crystalline structure of the middle layer of lysine. On the right the wafer easily flexes for biocompatibility and to induce the lysine crystal to create an electrical output. Scale is centimeters. Credit: Xudong Wang, University of Wisconsin-Madison Bioengineers have developed biocompatible generators that create...
by Ruhr-Universitaet-Bochum Central nervous system injuries cannot heal for a variety of reasons. Therefore, lifelong disabilities remain. Credit: RUB, Kramer Three main causes for the inability of injured nerves of the central nervous system, or CNS, to regenerate have been known to date: the insufficient activation of a regeneration program in injured nerve cells that stimulates...
by Linda Koffmar, Uppsala University Credit: Circulation Research (2021). DOI: 10.1161/CIRCRESAHA.120.318380 Cardiovascular disease, the most common cause of death, is the result of oxygen deprivation as blood perfusion to affected tissue is prevented. To halt the development of the disease and to promote healing, re-establishment of blood flow is crucial. Researchers at Uppsala University have now discovered that one of the...
Increases in chronic inflammation—not the passage of time—is the main reason why injured bones do not heal as well with age. This is the finding of a study in mice and humans published March 18 in the Proceedings of the National Academy of Sciences (PNAS). The results revolve around the known breakdown, due to wear and tear,...
MADISON – A new, low-cost wound dressing developed by University of Wisconsin-Madison engineers could dramatically speed up healing in a surprising way. The method leverages energy generated from a patient’s own body motions to apply gentle electrical pulses at the site of an injury. IMAGE: MATERIALS SCIENCE AND ENGINEERING PROFESSOR XUDON WANG FITS A NEW WOUND DRESSING...
Researchers at Northwestern University have developed a thermoresponsive hydrogel bandage. The hydrogel is liquid at room temperature but changes into a semi-solid gel at body temperature when in contact with a wound, meaning it conforms to the wound shape. The gel contains an amino acid sequence that stimulates the body’s own healing process. The researchers hope that the...
The findings suggest that boosting signals in certain cells and not in others might even help treat colon cancer WEIZMANN INSTITUTE OF SCIENCE Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute. Weizmann Institute of Science researchers are proposing a way around this complexity. In a study in...
