by Massachusetts Eye and Ear Infirmary Credit: Unsplash/CC0 Public Domain Researchers from Mass Eye and Ear have developed a word-score model capable of estimating the amount of hidden hearing loss in human ears. In a new study published June 23 in Scientific Reports, a team of researchers at Mass Eye and Ear’s Eaton-Peabody Laboratories determined average speech scores...
by University of Miami Credit: Pixabay/CC0 Public Domain Researchers at the John T. Macdonald Department of Human Genetics and John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families. The gene variation mostly affects the...
by King’s College London Evaluation of enrichment of common-variant hearing loss GWAS results in scRNA-seq mouse datasets. Schematic of the mouse cochlea (A) and the mouse brain (B) regions used for the enrichment analysis. Abbreviations: Amg, amygdala; Cbx, cerebellum; Ctx, cerebral cortex; DC, Deiters’ cells; Hi, hippocampus; Hy, hypothalamus; IHC, inner hair cells; Mb, midbrain;...
AMERICAN COLLEGE OF MEDICAL GENETICS AND GENOMICS The American College of Medical Genetics and Genomics (ACMG) has released a new Clinical Practice Resource that will help direct the treatment of patients with hearing loss: “Clinical Evaluation and Etiologic Diagnosis of Hearing Loss: A Clinical Practice Resource of the American College of Medical Genetics and Genomics.”...
By ZACH WINN, MASSACHUSETTS INSTITUTE OF TECHNOLOGY APRIL 9, 2022 These images show cellular regeneration, in pink, in a preclinical model of sensorineural hearing loss. The control is on the left and the right has been treated. Credit: Hinton AS, Yang-Hood A, Schrader AD, Loose C, Ohlemiller KK, McLean WJ. MIT spinout Frequency Therapeutics’ drug candidate stimulates the...
Lindsay Kalter March 31, 2022 The World Health Organization is investigating rare instances of hearing loss and other auditory disturbances associated with COVID-19 vaccinations – primarily the Pfizer-BioNTech shots, according to a report from WHO. Of 11 billion doses given, a WHO newsletter reported 164 cases of hearing loss worldwide among people who had received Pfizer-BioNTech, Moderna or AstraZeneca shots. There...
by IOS Press Credit: Unsplash/CC0 Public Domain A new study led by a Baycrest clinician-scientist titled “Enhancing Clinical Visibility of Hearing Loss in Cognitive Decline” demonstrated that point of care screening for hearing loss in patients of a memory clinic raised physicians’ awareness of its high prevalence among their patients and led to more frequent...
by Children’s Hospital Boston This scanning electron micrograph shows sensory outer hair cells, which are required for cochlear amplification and normal hearing. The image at left shows a disorganized sensory hair cell from the inner ear from a mouse with a mutation in the Strc gene; as a result, the cell is missing scaffolding links...
UNIVERSITY OF SOUTHERN CALIFORNIA – HEALTH SCIENCES IMAGE: JOHN OGHALAI, MD, AN OTOLARYNGOLOGIST WITH KECK MEDICINE OF USC AND CHAIR OF THE USC CARUSO DEPARTMENT OF OTOLARYNGOLOGY – HEAD AND NECK SURGERY, IS THE LEAD AUTHOR OF THE STUDY. CREDIT: RICARDO CARRASCO III LOS ANGELES — Exposure to loud noise, such as a firecracker or...
A team of Harvard Medical School scientists at Massachusetts Eye and Ear, led by Albert Edge and Yushi Hayashi, has identified the mechanism that can lead to deafness in the rare syndrome Norrie disease. The researchers found that the Norrie disease protein (NDP), lacking in patients with the disease, is essential for the maintenance and survival of hair...
