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Revealing the individual immune cells inside the plaque that causes life-threatening heart attacks
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Revealing the individual immune cells inside the plaque that causes life-threatening heart attacks

KOBE UNIVERSITY IMAGE: COMPARISON OF SINGLE-CELL RNA SEQUENCING RESULTS FOR CHRONIC CORONARY SYNDROME AND ACUTE CORONARY SYNDROME. CREDIT: FIGURE DERIVED FROM THE PAPER PUBLISHED IN CIRCULATION (2022) (DOI: 10.1161/CIRCULATIONAHA.121.058414) Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term...

Mending the heart: Blocking DYRK1a could lead to better heart attack outcomes
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Mending the heart: Blocking DYRK1a could lead to better heart attack outcomes

by Josh Barney, University of Virginia Credit: Pixabay/CC0 Public Domain University of Virginia School of Medicine scientists have identified a potential way to improve heart function after heart attacks—and it could involve a drug extracted from plants commonly used as folk medicine. The researchers, led by Dr. Matthew J. Wolf, found that blocking a particular...

Game-changing new therapy to lower cholesterol and stabilize plaques associated with heart attack
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Game-changing new therapy to lower cholesterol and stabilize plaques associated with heart attack

by Monash University Credit: JACC: Cardiovascular Imaging (2022). DOI: 10.1016/j.jcmg.2022.03.002 A novel new therapy has been found to reduce harmful plaque in arteries and change its composition so it is less likely to rupture and cause a heart attack, following a clinical trial led by the Victorian Heart Institute (VHI) at Monash University. The HUYGENS study treated...

If blood pressure rises upon standing, so may risk for heart attack
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If blood pressure rises upon standing, so may risk for heart attack

by American Heart Association Credit: Unsplash/CC0 Public Domain Among young and middle-aged adults with high blood pressure, a substantial rise in blood pressure upon standing may identify those with a higher risk of serious cardiovascular events, such as heart attack and stroke, according to new research published today in the American Heart Association’s peer-reviewed journal Hypertension....

Research team develops a smartphone app to calculate genetic risk for heart attack
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Research team develops a smartphone app to calculate genetic risk for heart attack

by The Scripps Research Institute Scientists at the Scripps Research Translational Institute developed the MyGeneRank mobile app that can provide study participants with their unique genetic risk score for coronary artery disease. Credit: Scripps Research A Scripps Research team has developed a smartphone app that can calculate users’ genetic risk for coronary artery disease (CAD)—and...

In older adults, money problems increase risk of death after heart attack
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In older adults, money problems increase risk of death after heart attack

by Ashley P. Taylor, Yale University Mortality rates across 180 days after acute myocardial infarction by financial strain status. Cumulative hazards for mortality across each level of financial strain are shown. The light blue line indicates severe financial strain, or those who reported not having enough monthly income to make ends meet. The orange line...

Smoking may increase risk of heart attack via enhanced platelet activity
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Smoking may increase risk of heart attack via enhanced platelet activity

by University of Bristol Credit: Unsplash/CC0 Public Domain Smoking cigarettes may increase the risk of a heart attack by activating a gene that affects blood clotting, according to a new study by scientists at the University of Bristol. The study, published in Circulation Research, used a multidisciplinary approach involving four different study designs, including data from...

New study could inform treatment and prevent heart attack in diabetic patients
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New study could inform treatment and prevent heart attack in diabetic patients

by Baker Heart and Diabetes Institute  Myocardial Infarction or Heart Attack. Credit: Blausen Medical Communications/Wikipedia/CC-A 3.0 A new study by researchers at the Baker Heart and Diabetes Institute and Monash University could help inform treatment and prevent serious events like a heart attack or death in diabetic patients at high risk of serious cardiovascular events....

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A potential protector against a mild heart attack’s aftereffects on metabolism

OHIO STATE UNIVERSITY COLUMBUS, Ohio – A new study in mice shows transplanted brown fat can reduce type 2 diabetes risk factors after a heart attack, an encouraging finding for scientists who hope to apply the so-called “good” fat’s beneficial properties to drugs that can help prevent health problems. In the study, transplanting brown fat...