by Leah Eisenstadt, Broad Institute of MIT and Harvard Credit: Susanna Hamilton, Broad Communications Over the past decade, researchers have been developing polygenic scores—calculations of a person’s likelihood of getting a disease based on the millions of small genetic differences across their genome. The accuracy of these scores has improved for some diseases and groups of...
The gut microbiome may influence heart health, research shows. Laura Herrera/Stocksy Over the past few years, researchers have discovered more details on how the body’s gut microbiome affects its overall health. An unhealthy gut microbiome, for example, has been linked to a variety of diseases. Researchers from the University of Wisconsin–Madison have now identified specific bacteria in the...
Some bacteria in the guts of humans and mice may help control plaque buildup in arteries, the leading cause of cardiovascular disease, by gobbling up a group of inflammatory chemicals before they can circulate. New research from the University of Wisconsin–Madison and collaborators worldwide identified microbes able to break down uric acid in the low-oxygen environment of the...
by Duke-NUS Medical School Vascularization of human muscle grafts. a Schematic illustration of: (i) CCP generation; (ii) permanent MI infarction; (iii) intramyocardial transplantation of CCP; (iv) post-transplantation MRI and CT scans, and (v) euthanization at 4 or 12 weeks post-transplantation. At 4 weeks, the human grafts showed disorganized staining of b TNNT2 (red) Scale bar = 20 μm, d ACTN2 (red) and MLC2v...
by NYU Langone Health Atherosclerosis is a condition affecting the cardiovascular system. If atherosclerosis occurs in the coronary arteries (which supply the heart) the result may be angina pectoris, or in worse cases a heart attack. Credit: Wikipedia/CC BY 3.0 An experimental drug already tested as a potential treatment for cancer, lung, and Alzheimer’s disease may...
by Baker Heart and Diabetes Institute Credit: JACC: Cardiovascular Imaging (2023). DOI: 10.1016/j.jcmg.2023.03.007 Visualizing early heart disease using cardiac imaging helps with patient understanding of risk and adherence to medication and lifestyle change, according to a new study by researchers from the Baker Heart and Diabetes Institute and the Menzies Institute for Medical Research. Researchers found patients who viewed...
by Impact Journals LLC Univariate associations of minor alleles of four SNPs from the MLXIPL gene with AD and CHD in two samples drawn from US cohorts (A) and UK biobank (B). Credit: Aging (2023). DOI: 10.18632/aging.204665 A new research paper titled “Exogenous exposures shape genetic predisposition to lipids, Alzheimer’s, and coronary heart disease in the MLXIPL...
by Michael Merschel, American Heart Association Distribution of self-rated American and South Asian identity scores in the mediators of atherosclerosis in South Asians living in America participants. Credit: Journal of Asian Health (2023). DOI: 10.59448/jah.v3i2.35 Like many people of South Asian ancestry, Anjana Srivastava can offer a long list of family members who’ve had heart disease. “My grandfathers....
Reviewed by Emily Henderson, B.Sc. Mar 27 2023 Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD). A new scientific statement, published today in the American Heart Association journal Circulation: Genomic and Precision Medicine, aims to help individuals and health care professionals...
by Columbia University Irving Medical Center Credit: Pixabay/CC0 Public Domain A new study by Columbia University researchers suggests that cholesterol-lowering drugs called statins have the potential to reduce heart disease in people with obstructive sleep apnea, regardless of the use of CPAP machines during the night. The study is published in the journal Annals of the American Thoracic...
