by Ana María Rodríguez, Baylor College of Medicine Credit: CC0 Public DomainHeart failure remains the leading cause of mortality in the U.S. During a heart attack blood stops flowing into the heart. Without oxygen, part of the heart muscle dies. The heart muscle does not regenerate; instead, it replaces dead tissue with a scar made of...
by Ana María Rodríguez, Baylor College of Medicine Credit: Pixabay/CC0 Public DomainIn 2020, heart failure affected about 6.5 million people in the U.S. and 23 million around the world. Despite recent advances, the five-year survival rate remains approximately 50%, indicating an urgent need for a novel perspective for treating this condition. A new approach described in...
UCLA Health researchers say findings may have implications for heart failure treatmentPeer-Reviewed Publication UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES A new study sheds light on how autophagy, the body’s process for removing damaged cell parts, when impaired, can play a role in causing heart failure. The research team led by Dr. E. Dale...
by American College of Physicians Credit: Pixabay/CC0 Public DomainA new protein risk score developed to predict the risk of death for persons with heart failure (HF) has demonstrated good calibration and may help clinicians better stratify mortality risk in these patients. The score is published in Annals of Internal Medicine. Heart failure is a complex clinical...
by Elana Gotkine Heart failure is causally associated with chronic kidney disease (CKD), according to a study published online Dec. 11 in PLOS ONE. Junyu Zhang, from Hunan University of Chinese Medicine in Changsha, China, and colleagues used data from European populations, including 930,014 controls and 47,309 cases of heart failure from the HERMES consortium...
by American Heart Association Credit: Unsplash/CC0 Public Domain Using marijuana regularly may raise the risk for heart failure, stroke or heart attack even after accounting for other cardiovascular risk factors such as Type 2 diabetes, high blood pressure and obesity, according to two preliminary studies to be presented at the American Heart Association’s Scientific Sessions 2023. The...
Katherine Lewin | News Reporter Novo Nordisk’s GLP-1 Wegovy has shown cardiovascular benefit again, this time in the Phase III STEP HFpEF trial, on top of the expected weight loss, the company announced at the European Society of Cardiology (ESC) Congress today. Against placebo, 2.4 mg of Wegovy (semaglutide) showed “large” reductions in heart failure-related...
by Janosch Deeg, Max Delbrück Center for Molecular Medicine Cardiomyocytes with stained mitochondria (red), sarcomeres (green) and nuclei (blue). Credit: Klaassen Lab, Max Delbrück CenterWhen the PRDM16 gene mutates, heart muscle cells undergo changes in their metabolism. This increases the risk of congenital heart failure in women more than men, as a ECRC research team led...
Patrick Campbell Conference |European Society of Cardiology CongressJaved Butler, MD, discusses the overall results of the STEP-HFpEF trial, how he interprets the reduction in adjudicated heart failure events, and how the community’s recent experience with SGLT2 inhibitors might inform uptake strategies for semaglutide 2.4 mg. The understanding and management of heart failure with preserved ejection...
by Medical University of South Carolina Dr. del Monte from the Medical University of South Carolina enjoys a break from her research into Alzheimer’s disease and heart failure. Credit: The photo was taken by Sarah Pack from the Medical University of South Carolina. The passing of June’s summer solstice, the longest day of the year, prompts reflection on all of the...
