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New study shows regular exercise pre-hospitalization is linked to better outcomes in heart failure

Researchers showed that older patients with heart failure who exercised regularly before hospitalization had better physical function and lower mortalityPeer-Reviewed Publication Juntendo University Research Promotion Center FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail image:  Regular exercise before hospitalization significantly improves strength, physical function, and survival rates in older adults with heart failure, highlighting its importance for effective risk assessment.view more  Credit: Dr....

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Study shows that continued medication important for heart failure patients

by Karolinska Institutet Credit: Pixabay/CC0 Public Domain Patients who have been treated for heart failure and experience an improvement in their pump function are still at higher risk of heart-related death or hospitalization if they stop taking heart failure medications. This is according to a new study from Karolinska Institutet published in Circulation. “Our finding raises awareness...

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Calcium channel inhibition promotes cardiac regeneration, offering hope for heart failure treatment

by Kimberly R. Holloway, Baylor College of Medicine LTCC inhibition by RRAD or nifedipine induced CM cell cycle by modulating calcineurin activity. Credit: npj Regenerative Medicine (2025). DOI: 10.1038/s41536-025-00389-z Researchers report a discovery in cardiac regeneration that offers new hope for the treatment of ischemic heart failure. Published in npj Regenerative Medicine, the study reveals a novel approach to...

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‘A Turning Point’ in Heart Failure

Carolyn Brown February 26, 2025 3235 For decades, physicians had little to offer patients who have heart failure with preserved ejection fraction (HFpEF), which is a growing global health problem with a grim death rate in the 5 years after diagnosis. But that started to change in 2021, when a drug trial showed benefits in...

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A step toward precision medicine: New drug targets for heart failure

By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Benedette Cuffari, M.Sc.Feb 14 2025 A groundbreaking study in Nature Cardiovascular Research uncovers promising drug targets for heart failure (HF) and its subtypes, offering new hope for precision medicine in cardiology. Study: Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction. Image Credit: Owlie Productions / Shutterstock.com A...

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Smartwatches may soon detect congestive heart failure

by Tampere University Illustration of the classification pipeline. See Fig. 5 for more details about DDFA density and DDFA α(HR, s). Credit: Heart Rhythm O2 (2025). DOI: 10.1016/j.hroo.2025.01.014 Researchers at Tampere University have achieved a major milestone in diagnosing heart diseases. According to their new study published in Heart Rhythm O2, congestive heart failure can be reliably detected by analyzing the...

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New AI Tool Identifies Risk of Future Heart Failure

Posted Today In a new study led by Yale School of Medicine’s Cardiovascular Data Science (CarDS) Lab, researchers developed an artificial intelligence (AI) tool that can identify individuals at high risk of developing heart failure using electrocardiogram (ECG) images. The new tool enables earlier identification of heart failure, potentially reducing hospitalizations and premature death, the researchers said....

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Study uncovers new link between infections and heart failure

by Jeremy Olson Credit: CC0 Public Domain People hospitalized for infections—almost any infections—are at substantially increased risk years later for heart failure, according to collaborative research by the University of Minnesota and Mayo Clinic. The study of more than 14,000 people over two decades doesn’t establish cause and effect, but advocates said Thursday that it...

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Stem-cell ‘heart patch’ shows promise for heart failure treatment

by Lena Bösch, Universitätsmedizin Göttingen – Georg-August-Universität The heart patch is produced from induced pluripotent stem cells derived from heart muscle cells in a collagen hydrogel. Credit: UMG/Eva Meyer-Besting Results from rhesus macaques provide solid ground for a first-in-human investigation of heart repair with stem cell-derived engineered heart muscle. The study is a milestone for...

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Enzyme ALPK2: A therapeutic target for a lethal form of heart failure

by Nagoya University A new therapeutic target for a lethal form of heart failure: ALPK2. Credit: 2024 Federation of American Societies for Experimental Biology (FASEB). Researchers from the Nagoya University Graduate School of Medicine identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically expressed in the heart. They found that the enzyme may prevent a stiff...