Tag: <span>heart failure</span>

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Delays in heart failure diagnosis for chronically ill people leads to much worse outcomes

by University of Leicester More people are being diagnosed in hospital with heart failure than in the community because vital heart failure symptoms are being missed. A major Leicester Diabetes Centre study, which has looked at data collected across a 20-year period, has found that over 70 percent of people are not being diagnosed with...

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Atrial fibrillation common and incurable, but controllable

by Scott Gilbert,  Pennsylvania State University One of the most common problems cardiologists handle is atrial fibrillation, also called AFib or AF. AFib is an abnormal or irregular heartbeat that can lead to blood clots, stroke, heart failure and other heart-related complications. As many as 6 million people in the United States and 33 million people...

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The Intestine Responds to Heart Failure by Enhanced Mitochondrial Fusion through Glucagon-like Peptide-1 Signaling

Aims Glucagon-like peptide-1 (GLP-1) is a neuroendocrine hormone secreted by the intestine. Its receptor (GLP-1R) is expressed in various organs, including the heart. However, the dynamics and function of the GLP-1 signal in heart failure remains unclear. We investigated the impact of the cardio-intestinal association on hypertensive heart failure using miglitol, an α-glucosidase inhibitor known...

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Researchers discover how to treat diastolic heart failure

Research out of University Minnesota Medical School and published in the Journal of Clinical Investigation Insight uncovers what causes diastolic heart failure and how it can be treated. In the article, “Magnesium supplementation improves diabetic mitochondrial and cardiac diastolic function,” author Samuel Dudley, MD, Ph.D., Academic Chief of Cardiology at the University of Minnesota Medical...

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For older adults with heart failure: Can taking too many medications reduce abilities?

As we age, we tend to develop a number of chronic health conditions and concerns. Often, managing health problems can mean that older adults may take many different medications. When older adults take five or more medicines (a scenario health experts call “polypharmacy”, it can increase the risk of harmful side effects. Polypharmacy can contribute...

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Diabetes drug prevents heart failure

Boston, MA — In the largest trial to date to assess cardiovascular outcomes for an important class of diabetes medications, researchers have found that dapagliflozin markedly reduced the risk of hospitalization for heart failure in a broad population of patients with diabetes. This benefit was seen across the study population, including in patients who did...

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In patients with heart failure, anxiety and depression linked to worse outcomes

WOLTERS KLUWER HEALTH July 6, 2018 – Symptoms of depression and anxiety are present in about one-third of patients with heart failure – and these patients are at higher risk of progressive heart disease and other adverse outcomes, according to a review and update in the July/August issue of Harvard Review of Psychiatry. The journal is published...

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New target for treating heart failure identified

Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure, found researchers from the Perelman School of Medicine at the University of Pennsylvania. This Nature...