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Diabetes drug prevents heart failure

Boston, MA — In the largest trial to date to assess cardiovascular outcomes for an important class of diabetes medications, researchers have found that dapagliflozin markedly reduced the risk of hospitalization for heart failure in a broad population of patients with diabetes. This benefit was seen across the study population, including in patients who did...

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In patients with heart failure, anxiety and depression linked to worse outcomes

WOLTERS KLUWER HEALTH July 6, 2018 – Symptoms of depression and anxiety are present in about one-third of patients with heart failure – and these patients are at higher risk of progressive heart disease and other adverse outcomes, according to a review and update in the July/August issue of Harvard Review of Psychiatry. The journal is published...

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New target for treating heart failure identified

Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure, found researchers from the Perelman School of Medicine at the University of Pennsylvania. This Nature...

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Cardiac Stem Cell Therapies: The Next Revolution in Heart Failure Treatment

Guest Post: This is a guest article by Clifford M. Thornton, a Certified Cardiovascular Technologist, experienced Echocardiographer Technician, and journalist in the cardiac and medical device fields. His articles have been published in Inventor’s Digest, Global Innovation Magazine, and Modern Health Talk. He is enthusiastic about progress with cardiac stem cell therapies and their role in...

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Heart failure patients with a higher protein intake live longer

Heart failure patients who consume more protein live longer, according to research presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. Elderly adults need to maintain muscle mass for optimal health. However, most lose muscle mass as they age and are less efficient at using dietary protein to build muscle....

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A paradigm shift in heart failure treatment?

A small, preliminary study could trigger a paradigm shift in the treatment of heart failure. The late-breaking research is published today in Circulation and presented at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. The study suggests that heart failure may be caused by inappropriate fluid shifts in some patients...

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Blocking matrix-forming protein might prevent heart failure

Few treatment options for leading cause of death CINCINNATI – Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers at the Cincinnati Children’s Heart Institute report in the journal Circulation testing a manufactured peptide called...

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Scientists identify a promising target for the treatment of heart failure

Stained heart sections from wild-type mice and knockout mice that do not express OMA1. Wild-type mice exposed to ISO, which induces heart failure, exhibited collagen lesions indicative of heart cell death (top right), while knockout mice  Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) led by Dr. José Antonio Enríquez have described...