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New protein risk score shows strong clinical utility for predicting death from heart failure
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New protein risk score shows strong clinical utility for predicting death from heart failure

by American College of Physicians Credit: Pixabay/CC0 Public DomainA new protein risk score developed to predict the risk of death for persons with heart failure (HF) has demonstrated good calibration and may help clinicians better stratify mortality risk in these patients. The score is published in Annals of Internal Medicine. Heart failure is a complex clinical...

Heart failure causally linked to chronic kidney disease
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Heart failure causally linked to chronic kidney disease

by Elana Gotkine Heart failure is causally associated with chronic kidney disease (CKD), according to a study published online Dec. 11 in PLOS ONE. Junyu Zhang, from Hunan University of Chinese Medicine in Changsha, China, and colleagues used data from European populations, including 930,014 controls and 47,309 cases of heart failure from the HERMES consortium...

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Marijuana use linked with increased risk of heart attack, heart failure

by American Heart Association Credit: Unsplash/CC0 Public Domain Using marijuana regularly may raise the risk for heart failure, stroke or heart attack even after accounting for other cardiovascular risk factors such as Type 2 diabetes, high blood pressure and obesity, according to two preliminary studies to be presented at the American Heart Association’s Scientific Sessions 2023. The...

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Once again, Novo’s semaglutide shows cardiovascular benefit, weight loss — this time in adults with heart failure

Katherine Lewin | News Reporter Novo Nordisk’s GLP-1 Wegovy has shown cardiovascular benefit again, this time in the Phase III STEP HFpEF trial, on top of the expected weight loss, the company announced at the European Society of Cardiology (ESC) Congress today. Against placebo, 2.4 mg of Wegovy (semaglutide) showed “large” reductions in heart failure-related...

Mutation puts women at higher risk of heart failure
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Mutation puts women at higher risk of heart failure

by Janosch Deeg, Max Delbrück Center for Molecular Medicine Cardiomyocytes with stained mitochondria (red), sarcomeres (green) and nuclei (blue). Credit: Klaassen Lab, Max Delbrück CenterWhen the PRDM16 gene mutates, heart muscle cells undergo changes in their metabolism. This increases the risk of congenital heart failure in women more than men, as a ECRC research team led...

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Semaglutide for HFpEF? Breaking Down the STEP-HFpEF Trial, with Javed Butler, MD

Patrick Campbell Conference |European Society of Cardiology CongressJaved Butler, MD, discusses the overall results of the STEP-HFpEF trial, how he interprets the reduction in adjudicated heart failure events, and how the community’s recent experience with SGLT2 inhibitors might inform uptake strategies for semaglutide 2.4 mg. The understanding and management of heart failure with preserved ejection...

Head to heart: Linking Alzheimer’s disease to heart failure
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Head to heart: Linking Alzheimer’s disease to heart failure

by Medical University of South Carolina Dr. del Monte from the Medical University of South Carolina enjoys a break from her research into Alzheimer’s disease and heart failure. Credit: The photo was taken by Sarah Pack from the Medical University of South Carolina. The passing of June’s summer solstice, the longest day of the year, prompts reflection on all of the...

Predicting heart failure with longitudinal urine patterns and changing kidney markers
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Predicting heart failure with longitudinal urine patterns and changing kidney markers

by Osaka University Credit: European Journal of Heart Failure (2023). DOI: 10.1002/ejhf.2925 They say that an ounce of prevention is worth a pound of cure; knowing which preventive treatment to administer to which patient could undoubtedly up that yield. Now, an international research team led by Osaka University has identified an important treatment target that could help prevent patients from...

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PCPs Key to Heart Failure Care After Discharge

Lori Youmshajekian July 05, 2023 Madeline Sterling, MD, knew something was wrong when she heard her patient’s voice on the phone. The patient was breathing too fast and sounded fatigued. Like many people with heart failure, this patient had several comorbidities: diabetes, high blood pressure, and cancer, which was in remission. The patient had been in and out...

Could carpal tunnel syndrome fuel heart failure risk?
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Could carpal tunnel syndrome fuel heart failure risk?

by Alan Mozes Call it a hand signal of sorts. New research from Germany shows that the common nerve disorder carpal tunnel syndrome (CTS) may be a harbinger for heart failure among older folks. In a study of 164,000 people, those 60 years or older who had the condition, which causes pain, weakness and numbness in the hand and...