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Flu shots can protect patients with heart failure from death
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Flu shots can protect patients with heart failure from death

by McMaster University Credit: Unsplash/CC0 Public Domain Flu shots can save the lives of people with cardiovascular disease by reducing cardiac complications as well as preventing influenza. An international study led by McMaster University researchers and published in The Lancet Global Health has found that influenza vaccines greatly reduce both pneumonia and cardiovascular complications in people with heart failure. “If...

AI transforms smartwatch ECG signals into diagnostic tool for heart failure
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AI transforms smartwatch ECG signals into diagnostic tool for heart failure

by ByTerri Malloy, Mayo Clinic Study participant engagement with the customized Mayo Clinic iPhone application. Credit: Nature Medicine (2022). DOI: 10.1038/s41591-022-02053-1 A study published in Nature Medicine reports the ability of a smartwatch ECG to accurately detect heart failure in nonclinical environments. Researchers at Mayo Clinic applied artificial intelligence (AI) to Apple Watch ECG recordings to identify patients with...

Researchers identify protein linked to heart failure in chemo patients
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Researchers identify protein linked to heart failure in chemo patients

by University of Manitoba Credit: CC0 Public Domain A team led by Dr. Lorrie Kirshenbaum from the Rady Faculty of Health Sciences and St. Boniface Hospital Research has identified a protein called TRAF2 that stops functioning in cancer patients taking the chemotherapy drug doxorubicin, which can result in heart failure. “The finding could lead to new...

How heart failure disrupts the cell’s powerhouse
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How heart failure disrupts the cell’s powerhouse

HOKKAIDO UNIVERSITY IMAGE: FROM LEFT: SHINGO TAKADA, HOKKAIDO UNIVERSITY AND HOKUSHO UNIVERSITY; SHINTARO KINUGAWA, KYUSHU UNIVERSITY; AND HISATAKA SABE, HOKKAIDO UNIVERSITY (PHOTOS: SHINGO TAKADA, SHINTARO KINUGAWA, HISATAKA SABE). CREDIT: SHINGO TAKADA, SHINTARO KINUGAWA, HISATAKA SABE Investigations in Japan have uncovered some molecular mechanisms behind mitochondrial dysfunction in chronic heart failure. Chronic heart failure causes the...

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Immune marker suPAR high in patients with heart failure, predicts risk and death

MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN For years, cardiologists have zeroed in on a hormone called BNP as a gold standard to determine if patients with heart failure are at risk of severe illness or death. It’s released by the heart in response to when the cardiac tissue stretches due to pressure. While the B-type natriuretic peptide,...

Genetic testing helps detect children likely to have heart failure and require a transplant
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Genetic testing helps detect children likely to have heart failure and require a transplant

by Centenary Institute Credit: Unsplash/CC0 Public Domain Genetic testing can diagnose cardiomyopathy—a disease of the heart muscle—in children and help detect who will have heart failure and require a transplant, a new study has found. Researchers at the Centenary Institute and the Murdoch Children’s Research Institute (MCRI) have shown that genetic testing for cardiomyopathy in children and their first...

Study identifies new prognostic biomarker for heart failure
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Study identifies new prognostic biomarker for heart failure

by  Perelman School of Medicine at the University of Pennsylvania Multivariable Cox Proportional-Hazards Models in the TOPCAT trial. Multivariable Cox proportional-hazards models that include endotrophin, NT-proBNP, and MAGGIC (Meta-Analysis Global Group in Chronic Heart Failure) risk score as predictors of (Panel A) the primary end point, (Panel B) death or heart failure–related hospital admission, and (Panel...

Common back ailment could be sign of heart failure
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Common back ailment could be sign of heart failure

by Columbia University Irving Medical Center Screening spinal stenosis patients undergoing surgery for protein deposits in their spine could identify people at risk of developing heart failure from deposits of the same protein in the heart. Image of transthyretin protein deposits in the heart. Credit: Mathew Maurer/Columbia University Irving Medical Center. Columbia researchers have found...

Acetazolamide helps treat volume overload in heart failure
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Acetazolamide helps treat volume overload in heart failure

For patients with acute decompensated heart failure, the addition of acetazolamide to loop diuretic therapy yields an increased incidence of successful decongestion, according to a study published online Aug. 27 in the New England Journal of Medicine to coincide with the European Society of Cardiology Congress 2022, held from Aug. 26 to 29 in Barcelona, Spain. Wilfried...

How pathogenic gene variants lead to heart failure
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How pathogenic gene variants lead to heart failure

by Max Delbrück Center for Molecular Medicine In this illustration, the diseased heart is displayed as a piñata being hit by a DNA bat to signify the genetic impact of the variants that were studied. Patient cells are illustrated as confetti flying out of the heart and the colors recall the five main genotypes discussed...