by Columbia University Irving Medical Center Screening spinal stenosis patients undergoing surgery for protein deposits in their spine could identify people at risk of developing heart failure from deposits of the same protein in the heart. Image of transthyretin protein deposits in the heart. Credit: Mathew Maurer/Columbia University Irving Medical Center. Columbia researchers have found...
Tag: <span>heart failure</span>
Acetazolamide helps treat volume overload in heart failure
For patients with acute decompensated heart failure, the addition of acetazolamide to loop diuretic therapy yields an increased incidence of successful decongestion, according to a study published online Aug. 27 in the New England Journal of Medicine to coincide with the European Society of Cardiology Congress 2022, held from Aug. 26 to 29 in Barcelona, Spain. Wilfried...
How pathogenic gene variants lead to heart failure
by Max Delbrück Center for Molecular Medicine In this illustration, the diseased heart is displayed as a piñata being hit by a DNA bat to signify the genetic impact of the variants that were studied. Patient cells are illustrated as confetti flying out of the heart and the colors recall the five main genotypes discussed...
Overly restrictive salt intake may worsen outcomes for common form of heart failure
by British Medical Journal Credit: CC0 Public Domain Restricting salt intake is considered a key component of heart failure treatment, but restricting it too much may actually worsen the outcomes for people with a common form of the condition, suggests research published online in the journal Heart. Younger people and those of Black and other ethnicities...
Atrial fibrillation after surgery is linked to an increased risk of hospitalization for heart failure
by European Society of Cardiology Associations between post-operative atrial fibrillation and incident heart failure hospitalizations. Credit: European Heart Journal People who develop an abnormal heart rhythm after surgery have an increased risk of subsequently being admitted to hospital with heart failure, according to a study of over 3 million patients, which is published in the European Heart Journal today....
Single-cell map of heart failure suggests possible therapeutic targets
by Allessandra DiCorato, Broad Institute of MIT and Harvard Fibroblasts, a kind of connective tissue cell in the heart, showing cell nuclei (gray), tubulin (red), and actin (green). Credit: Maria (Masha) Kost-Alimova and Michelle Melanson, Center for the Development of Therapeutics Scientists from the Precision Cardiology Lab (PCL) of the Broad Institute of MIT and...
Researchers identify, test novel drug that may stop heart failure progression
by The Ohio State University Credit: Unsplash/CC0 Public Domain Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a novel drug molecule that targets T-cells causing inflammation in heart failure patients, stopping further progression of the disease. During heart failure, T-cells, which are part of the immune system, go from...
Uncontrolled diabetes can advance heart failure from early stage to late stage
JOHNS HOPKINS MEDICINE Among older adults with early stage — also known as preclinical — heart failure, uncontrolled diabetes can substantially increase the risk of heart failure progression, according to a new Johns Hopkins-led study. Researchers found that controlling diabetes early in the heart failure process has immense potential to significantly prevent the progression to...
Long-term study finds cigarette smoking doubled risk of developing heart failure
JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH A new study from researchers at the Johns Hopkins Bloomberg School of Public Health found that people who smoked tobacco cigarettes developed heart failure at twice the rate of those who never smoked. This higher rate occurred in two major heart failure subtypes and confirms that cigarette...
Speech analysis app predicts worsening heart failure before symptom onset
EUROPEAN SOCIETY OF CARDIOLOGY Madrid, Spain – 21 May 2022: A voice analysis app used by heart failure patients at home recognises fluid in the lungs three weeks before an unplanned hospitalisation or escalation in outpatient drug treatment. The late breaking research is presented at Heart Failure 2022, a scientific congress of the European Society of...