by Texas Heart Institute Wls knock-down by CRISPR/Cas9 in cardiomyocytes promotes cardiac fibroblast proliferation during neonatal heart regeneration. Green indicates Vimentin-positive cardiac fibroblasts; red indicates proliferating cells with EdU labeling; blue indicates nuclei by DAPI staining. Credit: Texas Heart Institute The Texas Heart Institute has announced that a new study from its prolific Cardiomyocyte Renewal...
Cardiomyocyte proliferation during EAM. In adult mammal hearts, cardiomyoctyes do not proliferate following damage such as that caused by myocardial infarction. However, in some mammals, cardiomyocyte proliferation occurs. “Neonatal cardiomyocytes proliferate, and the cardiomyocytes of zebrafish proliferate through adulthood,” says Osaka University Professor Yasushi Fujio. However, hearts recover well from myocarditis, suggesting adult cardiomyocytes can proliferate...
