Posted Today UCLA scientists have identified the protein GPNMB as a critical regulator in the heart’s healing process after a heart attack. Heart muscle cells surrounding the damaged tissue after a heart attack. Image credit: Arjun Deb Lab/UCLA Using animal models, they demonstrate that bone marrow-derived immune cells called macrophages secrete GPNMB, which binds to the...
Tag: <span>Heart repair</span>
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Researchers uncover novel role of protein GPNMB in heart repair
by University of California, Los Angeles Heart muscle cells surrounding the damaged tissue after a heart attack. Credit: Arjun Deb Lab/UCLA UCLA scientists have identified the protein GPNMB as a critical regulator in the heart’s healing process after a heart attack. Using animal models, they demonstrated that bone marrow-derived immune cells called macrophages secrete GPNMB, which binds to...
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Which cells are involved in heart repair and how they communicate with each other
by Stefan Zorn, Medizinische Hochschule Hannover Dr. Marc Reboll (left) and Professor Dr. Kai Wollert. Credit: Karin Kaiser / MHH More than 300,000 people suffer a heart attack in Germany every year. In this case, the heart muscle is no longer supplied with sufficient blood and oxygen, and part of the heart muscle tissue dies...
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Heart repair and regeneration after a heart attack: A review
by Jeff Hansen, University of Alabama at Birmingham Credit: Pixabay/CC0 Public Domain Twenty years ago, clinicians first attempted to regenerate a failing human heart by injecting muscle myoblasts into the heart during a bypass operation. Despite high initial hopes and multiple experimental and clinical studies since then, outcomes have been neutral or marginally positive for...