A step toward future medical applications Kumamoto University image: This study successfully reproduced the developmental process of hematopoietic stem cells (HSCs) in an in vitro culture system using commercially available endothelial cell lines as feeder cells, without the serum. By adding just two signaling molecules, stem cell factor (SCF) and thrombopoietin (TPO), the researchers were...
Tag: <span>hematopoietic stem cells</span>
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More selective elimination of leukemia stem cells and blood stem cells
by University of Zurich Novel immunotherapy against leukaemia: Genetically modified immune cells (white) attack the cancer cells (orange). Credit: iStock/wildpixel Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now...
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Bacterial infection stresses hematopoietic stem cells
It has been thought that only immune cells would act as the line of defense during bacterial infection. However, recent research has revealed that hematopoietic stem cells, cells that create all other blood cells throughout an individual’s lifetime, are also able to respond to the infection. A collaboration between researchers from Japan and Switzerland found...