by St. Jude Children’s Research Hospital Graphical Abstract. Credit: Cell (2023). DOI: 10.1016/j.cell.2023.05.005 Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme. Free heme can cause significant inflammation and organ damage, leading to morbidity and mortality. Researchers from St. Jude Children’s Research Hospital discovered NLRP12, an innate immune pattern recognition receptor,...
