by Liu Jia, Chinese Academy of Sciences The proposed model for PHD3-mediated noncanonical CRTC2 hydroxylation-dependent activation of hepatic gluconeogenesis. Targeting PHD3 or CRTC2 hydroxylation may provide novel therapeutic avenues for the treatment of hyperglycemia and type 2 diabetes. Credit: Prof. Li’s team A team led by Prof. Li Yu from the Shanghai Institute of Nutrition and...
