September 23, 2024 by Research Society on Alcoholism Credit: Pixabay/CC0 Public DomainPeople with alcohol use disorder (AUD) who are at risk of advanced liver disease are less likely to be referred for liver evaluation and care if they present primarily with alcohol-related mental health issues or a mental health diagnosis, according to a study of...
Tag: <span>Hepatology</span>
Strong link found between abnormal liver tests and poor COVID-19 outcomes
New Haven, Conn. — Researchers at the Yale Liver Center found that patients with COVID-19 presented with abnormal liver tests at much higher rates than suggested by earlier studies. They also discovered that higher levels of liver enzymes — proteins released when the liver is damaged — were associated with poorer outcomes for these patients,...
New method developed for non-invasive risk assessment following hepatitis C recovery
by Johannes Angerer, Medical University of Vienna The chronic viral inflammation of the liver that occurs in hepatitis C results in the formation of inflexible scar tissue in the form of fibrosis/cirrhosis of the liver. This impedes the flow of blood through the organ, with resulting hypertension in the portal vein. In the majority of...
Serious complication of Crohn’s disease may be preventable in young people
by University of Michigan For children and young adults with Crohn’s disease, steroid-sparing therapies may help reduce the risk of developing a severe and common complication of the inflammatory bowel condition, a new study suggests. About one in three people with Crohn’s disease develop what’s known as a perianal fistula, which can be painful, difficult...
New global estimates for hepatitis D highlight need to step up response
by University of Liverpool University of Liverpool researchers have published new estimates of the global burden of hepatitis D, and are calling for more efforts to tackle the ‘forgotten’ virus. In a study published in the Journal of Hepatology, Professor Anna Maria Geretti and Dr. Alexander Stockdale, in collaboration with researchers from the World Health...
TGF-β-driven reduction of CYGB is associated with oxidative DNA damage of HSCs in NASH
In the 2020 April 21 issue of Journal of Hepatology, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis (NASH) with fibrosis and suggested a possibility of the new therapy using cytoglobin (CYGB) inducer for...
T2DM is risk factor for liver fibrosis progression in NAFLD
Toshifumi Tada, M.D., from Ogaki Municipal Hospital in Japan, and colleagues examined clinical risk factors for progression of liver fibrosis in patients with NAFLD. Data were included for 1,562 patients with NAFLD (aged 36 to 64 years) and less severe liver fibrosis (FIB-4 index, <1.3). The researchers found that 186 patients progressed to advanced fibrosis (FIB-4 index, >2.67) during follow-up. For progression to advanced fibrosis, the three-, five-, seven-, and 10-year cumulative incidence rates...
Liver illness strikes Latino children like a ‘silent tsunami’
by Rob Waters, Kaiser Health News Saira Diaz uses her fingers to count the establishments selling fast food and sweets near the South Los Angeles home she shares with her parents and 13-year-old son. “There’s one, two, three, four, five fast-food restaurants,” she says. “And a little mom-and-pop store that sells snacks and sodas and...
Overwhelming evidence shows hepatitis C treatment effective for people who inject drugs
Researchers are calling on an end to discriminatory health and illicit drugs policies, based on overwhelming evidence that new hepatitis C therapies are effective at curing the virus in people who inject drugs. Electron micrographs of hepatitis C virus purified from cell culture. Scale bar is 50 nanometers. Credit: Center for the Study of Hepatitis...