by American Society for Biochemistry and Molecular Biology Enpp2 gene expression and autotaxin protein levels in jejunum. A. Enpp2 gene expression after feeding a chow diet (Chow) or Western diet (WD) for two weeks. Female Enpp2fl/fl/Ldlr-/- (Cont.) mice 3.1 ± 0.4 months of age (n = 5 mice per group) and female Enpp2fl/fl/Ldlr-/-/VilCre (iKO) mice 3.9 ±...
AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY IMAGE: MICROSCOPY IMAGE OF A MOUSE AORTA WITH ATHEROSCLEROTIC LESIONS. PLAQUES ARE SHOWN IN RED. CREDIT: SRINIVASA REDDY In a recent study, researchers determined that derivatives of natural emulsifiers such as phospholipids found in high-fat, high-cholesterol diets can promote atherosclerosis via gut bacteria interactions with the immune system. This...
Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm, a major cause of death and illness in the developing world. Parasitic worms affect up to a billion people, particularly in developing nations with poor sanitation. One of these parasites, known as “whipworm,” can cause long-lasting infections in the...
by University of Texas at Dallas A short term HFD regime does not induce the development of obesity nor hyperglycemia. (a) Mice were assigned either a HFD or chow diet at 6 weeks of age for 9 weeks. Weight assessment was performed weekly and blood glucose measurements were performed every weeks starting at week zero....
by Candy Gibson, University of South Australia Credit: Pixabay/CC0 Public Domain New research shows that fatty foods may not only be adding to your waistline but also playing havoc with your brain. An international study led by UniSA neuroscientists Professor Xin-Fu Zhou and Associate Professor Larisa Bobrovskaya has established a clear link between mice fed...
BECKMAN INSTITUTE FOR ADVANCED SCIENCE AND TECHNOLOGY IMAGE: JEFFERSON CHAN (LEFT), AN ASSOCIATE PROFESSOR OF CHEMISTRY AT THE UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN, AND ANUJ YADAV (RIGHT), A SENIOR RESEARCH ASSOCIATE, WERE PART OF A TEAM THAT DEMONSTRATED A DIRECT LINK BETWEEN A HIGH-FAT DIET AND HEIGHTENED NITRIC OXIDE LEVELS, WHICH CAN LEAD TO INCREASED RISK...
by University of Alabama at Birmingham Credit: Unsplash/CC0 Public Domain A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet. The therapy acts through sustained release of nitric oxide, a gaseous signaling chemical whose most important function in the body is relaxing...
by University of Texas Health Science Center at San Antonio Credit: CC0 Public Domain A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a groundbreaking paper authored by a team led by The University of Texas Health Science Center at San...
Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet shows that it is possible to eliminate the deleterious effects of a high-fat diet by lowering the levels of apolipoprotein CIII (apoCIII), a key regulator of lipid metabolism....
by Karolinska Institutet Credit: Unsplash/CC0 Public Domain Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet in Sweden shows that it is possible to eliminate the deleterious effects of a high-fat diet by lowering the levels of apolipoprotein...
