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High-Throughput Testing of Hundreds of Anti-Cancer Drug Combinations
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High-Throughput Testing of Hundreds of Anti-Cancer Drug Combinations

MAY 11TH, 2023 CONN HASTINGS  MEDICINE, ONCOLOGY Researchers at ETH Zurich in Switzerland have developed a high-throughput screening method for anti-cancer drugs that they have called “pharmascopy”. To date, the researchers have tested the system with multiple myeloma samples, a cancer that has a poor prognosis and is difficult to treat because of drug resistance. In such cancers, finding...

New high-throughput method greatly expands view of how mutations impact cells
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New high-throughput method greatly expands view of how mutations impact cells

by Tom Ulrich, Broad Institute of MIT and Harvard Credit: DOI: 10.1038/s41587-021-01160-7 There are millions of mutations and other genetic variations in cancer. Understanding which of these mutations is an impactful tumor “driver” compared to an innocuous “passenger,” and what each of the drivers does to the cancer cell, however, has been a challenging undertaking....