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Histone protein influences both neurological disorder and cancer
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Histone protein influences both neurological disorder and cancer

by Will Doss, Northwestern University Mutations in a histone regulator protein are linked to both a rare neurodevelopmental disorder and to some cancers, according to a study published in the journal Genes and Development. The protein, PHIP/BRWD2, binds to three different histone modifications that are associated with active gene expression, which explains it’s two-sided impact,...