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Pharma firm urged to share new ‘game-changer’ HIV drug
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Pharma firm urged to share new ‘game-changer’ HIV drug

MAY 30, 2024 Microscopic image of an HIV-infected T cell. Credit: NIAID More than 300 politicians, health experts and celebrities on Thursday called for US pharmaceutical giant Gilead to allow cheap, generic versions of a promising new HIV drug to be produced so it can reach people in developing countries most affected by the deadly...

HIV drug may be linked to increased risk of hypertension
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HIV drug may be linked to increased risk of hypertension

by Boston University Credit: Unsplash/CC0 Public Domain In 2019, the World Health Organization formally recommended the drug dolutegravir (DTG) as the preferred antiretroviral therapy (ART) for people living with HIV in low and middle-income countries (LMICs), citing that it is more effective and tolerable, less costly, and less prone to developing drug resistance than the previously recommended...

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HIV drug stabilizes disease progression in metastatic colorectal cancer

MASSACHUSETTS GENERAL HOSPITAL BOSTON — New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer. Findings from the trial, published in Cancer Discovery, raise the possibility of an unexpected promising direction in cancer treatment, not just colorectal cancer. The trial included...

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Sensitive tests suggest low risk of drug resistance with dapivirine ring

New results presented at HIVR4P finds no dapivirine-associated resistance detected among women who acquired HIV while using dapivirine vaginal ring in ASPIRE MICROBICIDE TRIALS NETWORK MADRID, October 24, 2018 – A monthly vaginal ring that slowly releases an antiretroviral (ARV) drug called dapivirine is currently undergoing regulatory review. If approved, the dapivirine ring would be the first biomedical HIV prevention method developed...

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Gilead HIV drug aces phase 2, teeing up tussle with GSK

Gilead is looking to bictegravir to defend its HIV franchise against GSK Gilead has posted upbeat phase 2 data on its next-generation integrase inhibitor bictegravir in HIV patients. The drug more than held its own against GlaxoSmithKline’s dolutegravir, setting the stage for a larger-scale comparison in phase 3 and potential scrap for a multibillion-dollar market. The trial...