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Study: First sustained remission of HIV infection following a bone marrow transplant in absence of protective mutation
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Study: First sustained remission of HIV infection following a bone marrow transplant in absence of protective mutation

September 5, 2024 by Pasteur Institute Credit: CC0 Public DomainA total of seven individuals worldwide (two patients in Berlin and patients in London, Düsseldorf, New York, City of Hope and Geneva) are considered likely to have been cured or to be in long-term remission of HIV infection after receiving a bone marrow transplant to treat...

Chances of eliminating HIV infection increased by novel dual gene-editing approach
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Chances of eliminating HIV infection increased by novel dual gene-editing approach

by Temple University Credit: CC0 Public Domain Gene-editing therapy aimed at two targets—HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells—can effectively eliminate HIV infection, new research from the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) shows. The study, published online...

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Shorter weekly course of rifapentine-isoniazid associated with much higher treatment completion rates compared to longer daily course

Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the...

Monoclonal antibody prevents HIV infection in monkeys, study finds
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Monoclonal antibody prevents HIV infection in monkeys, study finds

by Franny White,  Oregon Health & Science University HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia An experimental, lab-made antibody can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows. The results will inform a future human clinical trial evaluating leronlimab as potential pre-exposure prophylaxis, or PrEP,...

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Single dose of antibodies can knock out HIV in newborns

Combination of 2 antibodies taken 30 hours after virus exposure prevents infection in baby monkeys Date:January 7, 2020 Source:Oregon Health & Science University Summary:A single dose of an antibody-based treatment can prevent HIV transmission from mother to baby, new nonhuman primate research suggests for the first time. This is the first time a single dose of broadly neutralizing antibodies given after viral exposure has been found to prevent infection...

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Russian ‘CRISPR-baby’ scientist has started editing genes in human eggs with goal of altering deaf gene

Denis Rebrikov also told Nature that he does not plan to implant gene-edited embryos until he gets regulatory approval. David Cyranoski An earlier version of this story and its headline incorrectly stated that Denis Rebrikov had started editing eggs from a woman with a mutation that causes deafness. Russian biologist Denis Rebrikov has started gene editing in eggs donated by women who can...

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Study links individual HPV types to HIV infection

UC Riverside-led study finds persons with any HPV type, more than one HPV type, or high-risk HPV are more likely to test HIV positive UNIVERSITY OF CALIFORNIA – RIVERSIDE IMAGE: BRANDON BROWN SEEN HERE AT HIS DESK.  CREDIT: GENEVIEVE CASANOVA, UC RIVERSIDE. RIVERSIDE, Calif. — An international research team led by a scientist at the University of California, Riverside, has for the first time identified individual types...

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Scientists develop rapid test for diagnosing tuberculosis in people with HIV

An international team that includes Rutgers scientists has made significant progress in developing a urine diagnostic test that can quickly, easily and inexpensively identify tuberculosis infection in people also infected with HIV. TB is the leading infectious disease killer in the world and the most common cause of death for people living with HIV, although...

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Novel approach to track HIV infection

HIV infecting a human cell.   Northwestern Medicine scientists have developed a novel method of tracking HIV infection, allowing the behavior of individual virions—infectious particles—to be connected to infectivity. The findings could help lead to the development of novel therapies for HIV prevention and treatment by providing a deeper understanding of the mechanisms of HIV’s...