by Elana Gotkine For people with HIV (PWH) and a history of suboptimal adherence to antiretroviral therapy, long-acting injectable treatment with cabotegravir and rilpivirine (LAI) is superior to oral standard of care (SOC), according to a study presented at the annual Conference on Retroviruses and Opportunistic Infections, held from March 3 to 6 in Denver....
Allison Shelley When the world needed a COVID vaccine, leading HIV investigators answered the call to intervene in the coronavirus pandemic. Now, efforts to discover the world’s first HIV vaccine are revitalized. “The body is capable of making antibodies to protect us from HIV,” says Yunda Huang, PhD, from the Fred Hutchinson Cancer Center in...
You know mRNA, now meet siRNAPeer-Reviewed Publication UNIVERSITY OF WATERLOO Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year. Now, University of Waterloo pharmacy associate professor Emmanuel Ho has developed a novel nanomedicine...
by Pasteur Institute The anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-gp140 SIV IgG (A) and IgA (E) in W4-treated and W24-treated CyMs. Comparison of anti-gp140 SIV IgG (B) and IgA (F) levels between W4- and W24-treated CyMs at baseline, on day 28 p.i.; at 6...
by National Institutes of Health Transmission electron micrograph of HIV-1 virus particles (red) budding and replicating from a segment of a chronically infected H9 cell (blue). Particles are in various stages of maturity; arc/semi-circles are immature particles that have started to form but are still part of the cell. Immature particles slowly change morphology into mat....
by Tulane University Credit: Pixabay/CC0 Public Domain Researchers at Tulane have developed a new and rapid test that can detect both HIV and tuberculosis at the same time with just a small amount of blood. In a paper published in Clinical Chemistry, researchers led by Tony Hu, Weatherhead Presidential Chair in Biotechnology Innovation and director of...
by Viviana Sofía Flores Rivera, Yale University Credit: Pixabay/CC0 Public DomainLenacapavir, an injection, has been approved by the FDA for multi-drug resistant HIV. HIV is not curable yet, but it can be treated successfully throughout someone’s lifespan. “And so, in the field, we want to ensure that the treatments we have—which for now are for...
by Alan Mozes Meningococcal disease—which includes meningitis—appears to be on the rise among Americans infected with HIV, new research reveals. Researchers stress that the risk to any one person remains exceedingly rare, regardless of their HIV status. Each year between 2017 and 2021 HIV-positive patients accounted for five to 15 cases of the bacterial disease,...
by Bruno Geoffroy, University of Montreal Throughout the course of antiretroviral therapy, HIV hides quietly in reservoirs inside CD4+ T lymphocytes, white blood cells that play a role in activating the immune system against infection. The existence of these viral sanctuaries explains why antiretroviral therapy has to be maintained throughout a patient’s lifetime in order to keep the virus...
by European Society of Clinical Microbiology and Infectious Diseases Credit: Pixabay/CC0 Public Domain Data on a test that can detect HIV, hepatitis B and hepatitis C from a single drop of blood is being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark, (April 15–18). More than one million people...
